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Gene Expression Data
Assay Details
Assay
Reference: J:23797 Goji J, et al., Expression of c-ErbB2 in human neuroblastoma tissues, adrenal medulla adjacent to tumor, and developing mouse neural crest cells. Am J Pathol. 1995 Mar;146(3):660-72
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6196361
Gene symbol: Erbb2
Gene name: erb-b2 receptor tyrosine kinase 2
Antibody: anti-c-ErbB2
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 4c: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: adrenal gland Strong Regionally restricted 4c Stronger expression in cytosol intra-adrenal chromoblasts than in extra-adrenal chromoblasts.
TS21: migrating neural crest Ambiguous Regionally restricted 4c No expression in extra-adrenal adrenoblasts.
TS21: testis Weak Regionally restricted 4c Faint expression in precursory seminiferous tubule of testis.

Specimen 4d: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: adrenal cortex Present Regionally restricted 4d Authors report expression confined to fetal cortex, but not in mature cortex.
TS24: adrenal medulla Trace 4d Very faint expression in adrenomedullary cells. No expression in chromaffin cells.
TS24: pretubular aggregate Present Regionally restricted 4d

Specimen P4 not shown: postnatal day 4 (more )
Structure Level Pattern Image Note
TS28: adrenal gland zona fasciculata Present
TS28: adrenal gland zona glomerulosa Absent

Specimen P7 not shown: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: adrenal gland zona reticularis Present
TS28: adrenal gland zona fasciculata Absent
TS28: adrenal gland zona glomerulosa Absent

Specimen E13 not shown: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: dorsal root ganglion Present First expression in dorsal ganglion at E13.

Specimen E14 not shown: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: dorsal root ganglion Strong Regionally restricted Intensive cytoplasmic expression atE14.

Specimen 5a: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: dorsal root ganglion Present Regionally restricted 5a Expression in cytosol of ganglion cells.
TS27: spinal cord ventral horn Present Regionally restricted 5a Expression in neurons in ventral horn.

Specimen 5b: postnatal day 4 (more )
Structure Level Pattern Image Note
TS28: dorsal root ganglion Present Regionally restricted 5b Expression in plasma membrane and cellular processes of ganglion cells. No expression in cytosol.
TS28: corticospinal tract Present Regionally restricted 5b Expression in ascending and descending tracts of spinal cord.

Specimen 6a: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: sympathetic ganglion Present Regionally restricted 6a Expression in cytoplasm of pre-aortic abdominal ganglion cells. Very faint expression in post-aortic ganglion.

Specimen 6c: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: sympathetic ganglion Present Regionally restricted 6c Expression in cytoplasm of both pre- and post-aortic abdominal ganglion cells.
TS27: muscle tissue Present Regionally restricted 6c Expression in muscle cells.
TS27: lymph node Present Regionally restricted 6c Expression in lymph node stromal cells.

Specimen 6d: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: sympathetic ganglion Present Regionally restricted 6d Expression in plasma membrane and cellular processes, but not in cytosol, of ganglion cells.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory