Frrs1l In situ reporter (knock in) Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:236939 Madeo M, et al., Loss-of-Function Mutations in FRRS1L Lead to an Epileptic-Dyskinetic Encephalopathy. Am J Hum Genet. 2016 Jun 2;98(6):1249-55
Assay type:	In situ reporter (knock in)
MGI Accession ID:	MGI:6196049
Gene symbol:	Frrs1l
Gene name:	ferric-chelate reductase 1 like

Reporter:	lacZ
	Direct Detection

Results

Specimen 3 upper left: postnatal adult; Frrs1l^{tm1b(EUCOMM)Hmgu}/Frrs1l⁺ (more

)

Structure	Level	Pattern	Image	Note
TS28: basal ganglia	Present		3_upper left	Highest expression.
TS28: cerebellum	Present		3_upper left	Highest expression.
TS28: hippocampus	Present		3_upper left	Highest expression.
TS28: neocortex layer	Present	Widespread	3_upper left	Highest expression. Expressed differentially throughout the layers.
TS28: anterior olfactory nucleus	Present		3_upper left
TS28: substantia nigra	Present		3_upper left
TS28: thalamus	Present		3_upper left

Specimen 3 upper middle: postnatal adult; Frrs1l^{tm1b(EUCOMM)Hmgu}/Frrs1l⁺ (more

)

Structure	Level	Pattern	Image	Note
TS28: spinal cord dorsal horn	Present		3_upper middle

Specimen 3 upper right: postnatal adult; Frrs1l^{tm1b(EUCOMM)Hmgu}/Frrs1l⁺ (more

)

Structure	Level	Pattern	Image	Note
TS28: trigeminal ganglion	Present		3_upper right

Specimen 3 middle: postnatal adult; Frrs1l^{tm1b(EUCOMM)Hmgu}/Frrs1l⁺ (more

)

Structure	Level	Pattern	Image	Note
TS28: epididymis	Present		3_middle
TS28: seminiferous tubule	Present		3_middle

Specimen 3 lower 1: embryonic day 12.5; Frrs1l^{tm1b(EUCOMM)Hmgu}/Frrs1l⁺ (more

)

Structure	Level	Pattern	Image	Note
TS20: forebrain	Present	Regionally restricted	3_lower 1	Expressed in the ventral forebrain.
TS20: embryo	Present	Regionally restricted	3_lower 1	Expressed in the ventral forebrain, but a lower level of expression was seen in the remainder of the embryos.

Specimen 3 lower 2: embryonic day 12.5; Frrs1l^{tm1b(EUCOMM)Hmgu}/Frrs1l⁺ (more

)

Structure	Level	Pattern	Image	Note
TS20: forebrain	Present	Regionally restricted	3_lower 2	Expressed in the ventral forebrain.
TS20: spinal cord	Weak		3_lower 2
TS20: embryo	Present	Regionally restricted	3_lower 2	Expressed in the ventral forebrain, but a lower level of expression was seen in the remainder of the embryos.

Specimen 3 lower 3: embryonic day 12.5; Frrs1l^{tm1b(EUCOMM)Hmgu}/Frrs1l⁺ (more

)

Structure	Level	Pattern	Image	Note
TS20: forebrain	Present	Regionally restricted	3_lower 3	Expressed in the ventral forebrain.
TS20: embryo	Present	Regionally restricted	3_lower 3	Expressed in the ventral forebrain, but a lower level of expression was seen in the remainder of the embryos.

Specimen 3 lower 4: embryonic day 12.5; Frrs1l^{tm1b(EUCOMM)Hmgu}/Frrs1l⁺ (more

)

Structure	Level	Pattern	Image	Note
TS20: spinal cord	Weak		3_lower 4
TS20: embryo	Present		3_lower 4	Lower level of expression was seen in the remainder of the embryos.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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