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Gene Expression Data
Assay Details
Assay
Reference: J:138613 Rock JR, et al., The transmembrane protein TMEM16A is required for normal development of the murine trachea. Dev Biol. 2008 Sep 1;321(1):141-9
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6194873
Gene symbol: Acta2
Gene name: actin alpha 2, smooth muscle, aorta
Antibody: Anti-smooth muscle alpha-Actin (clone 1A4)
Detection system: Cy3
Results
Specimen 3G: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: trachea mesenchyme Present Regionally restricted 3G Expression in population of smooth muscle cells dorsal to trachea (trachealis muscle). Cells were spindle-shaped and spanned entire dorsal aspect of developing trachea.

Specimen 3H: embryonic day 14.5; Ano1tm1Bdh/Ano1tm1Bdh (more )
Structure Level Pattern Image Note
TS22: trachea mesenchyme Present Regionally restricted 3H Authors state the distribution of expressing cells was disrupted in mutants. Globular distribution of expression in a cluster of cells dorsal to trachea.

Specimen S2A: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: trachealis Present S2A

Specimen S2B: embryonic day 18.5; Ano1tm1Bdh/Ano1tm1Bdh (more )
Structure Level Pattern Image Note
TS26: trachea smooth muscle Present Regionally restricted S2B Expression in smooth muscle cells with abnormal morphology. Globular distribution of expression in a cluster of cells dorsal to trachea.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/06/2026
MGI 6.24
The Jackson Laboratory