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Gene Expression Data
Assay Details
Assay
Reference: J:138613 Rock JR, et al., The transmembrane protein TMEM16A is required for normal development of the murine trachea. Dev Biol. 2008 Sep 1;321(1):141-9
Assay type: RNA in situ
MGI Accession ID: MGI:6194860
Gene symbol: Ano1
Gene name: anoctamin 1, calcium activated chloride channel
Results
Specimen 1A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: foregut epithelium Present Widespread 1A Expression throughout foregut endoderm and primary lung buds.
TS17: lung rudiment Present Widespread 1A Expression throughout foregut endoderm and primary lung buds.

Specimen 1B: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: bronchus epithelium Present 1B Expression persisted in proximal airway epithelium (trachea and conducting airways of lung).
TS19: trachea epithelium Present 1B Expression persisted in proximal airway epithelium (trachea and conducting airways of lung).
TS19: lung epithelium Present Regionally restricted 1B No expression at distal tips of peripheral lung epithelium

Specimen 1C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: bronchus epithelium Present 1C Expression persisted in proximal airway epithelium (trachea and conducting airways of lung).
TS20: trachea epithelium Present 1C Expression persisted in proximal airway epithelium (trachea and conducting airways of lung).
TS20: lung epithelium Present Regionally restricted 1C No expression at distal tips of peripheral lung epithelium

Specimen 1D: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: bronchus epithelium Present 1D Expression persisted in proximal airway epithelium (trachea and conducting airways of lung).
TS20: trachea epithelium Present 1D Expression persisted in proximal airway epithelium (trachea and conducting airways of lung).
TS20: lung epithelium Present Regionally restricted 1D No expression at distal tips of peripheral lung epithelium
TS20: trachea mesenchyme Strong Regionally restricted 1D Intense expression in mesenchyme dorsal to trachea.

Specimen 1E: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: trachea epithelium Present 1E
TS22: trachea mesenchyme Strong Regionally restricted 1E Intense expression in mesenchyme dorsal to trachea, which forms the trachealis muscle.
TS22: esophagus Present 1E

Specimen 1F: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: trachea epithelium Present 1F
TS24: trachea mesenchyme Strong Regionally restricted 1F Intense expression in mesenchyme dorsal to trachea, which forms the trachealis muscle.
TS24: aorta Present 1F
TS24: thymus Present 1F

Specimen 1G: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: lung epithelium Present Regionally restricted 1G Expression in distal epithelial cells of lung.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory