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Gene Expression Data
Assay Details
Assay
Reference: J:210661 Seto Y, et al., Characterization of Olig2 expression during cerebellar development. Gene Expr Patterns. 2014 May;15(1):1-7
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6194375
Gene symbol: Olig2
Gene name: oligodendrocyte transcription factor 2
Results
Specimen 2A,B,C: embryonic day 12.5 (more )
Note: Double labeled: green - Olig2; magenta - Ptf1a (assay MGI:6194382).
Structure Level Pattern Image Note
TS21: cerebellum Present Regionally restricted 2A , 2B , 2C Some of the Olig2 immunopositive cells were also labeled with Ptf1a, a marker for GABAergic neuron progenitors.
Specimen 3A,G: embryonic day 12.5 (more )
Note: Triple labeled: green - Olig2; blue - Ptf1a (assay MGI:6194387); red - Lhx1 (assay MGI:6194383) and Lhx5 (assay MGI:6194385).
Structure Level Pattern Image Note
TS21: cerebellum Present Regionally restricted 3G , 3A Triple labeling indicated that some Olig2-positive cells express Ptf1a (marker for GABAergic neuron progenitors) and other Olig2-positive cells express Lhx1 and Lhx5 (which mark postmitotic GABAergic neurons). The results indicate that Olig2 is expressed in both mitotic and postmitotic cells.
Specimen 3B,H: embryonic day 12.5 (more )
Note: Double labeled: green - Olig2; magenta - Lhx1 (assay MGI:6194384) and Lhx5 (assay MGI:6194386).
Structure Level Pattern Image Note
TS21: cerebellum Present Regionally restricted 3H , 3B Some Olig2-positive cells express Lhx1 and Lhx5 (which mark postmitotic GABAergic neurons).
Specimen 3D: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS21: cerebellum Present 3D
Specimen 3I: embryonic day 12.5 (more )
Note: Double labeled: green - Olig2; magenta - Ptf1a (assay MGI:6194382).
Structure Level Pattern Image Note
TS21: cerebellum Present Regionally restricted 3I Some Olig2-positive cells express Ptf1a (marker for GABAergic neuron progenitors).
Specimen 6D,E: embryonic day 12.5 (more )
Note: Double labeled: green - Olig2; magenta - Skor2 (assay MGI:6194657).
Structure Level Pattern Image Note
TS21: cerebellum Present Regionally restricted 6E , 6D Olig2 expression was distinct from that of Skor2, an early marker of Purkinje cells.
Specimen 6G,H: embryonic day 12.5 (more )
Note: Double labeled: green - Olig2; magenta - Skor2 (assay MGI:6194657).
Structure Level Pattern Image Note
TS21: cerebellum Present Regionally restricted 6H , 6G Olig2 expression was distinct from that of Skor2, an early marker of Purkinje cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
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