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Gene Expression Data
Assay Details
Assay
Reference: J:136068 Bridgewater D, et al., Canonical WNT/beta-catenin signaling is required for ureteric branching. Dev Biol. 2008 May 1;317(1):83-94
Assay type: RNA in situ
MGI Accession ID: MGI:6193844
Gene symbol: Lhx1
Gene name: LIM homeobox protein 1
Probe: Lim1 probe5
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 5C Wt: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: primitive collecting duct Present 5C Wt Expression in ureteric bud.
TS20: cap mesenchyme Present 5C Wt Expression in nephron progenitors.
Specimen 5C ub-/-: embryonic day 12.5; Ctnnb1tm2Kem/Ctnnb1tm2Kem, Tg(Hoxb7-cre)5526Cmb/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: primitive collecting duct Trace 5C b-cat ub-/- Marked reduction of expression in ureteric bud.
TS20: cap mesenchyme Present 5C b-cat ub-/- Expression in nephron progenitors.
Specimen 6 Lim1 Wt: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: collecting duct Present 6_Lim1 Wt Expression seen in ureteric cells.
Specimen 6 Lim1 ub-/-: embryonic day 13.5; Ctnnb1tm2Kem/Ctnnb1tm2Kem, Tg(Hoxb7-cre)5526Cmb/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: collecting duct Absent 6_Lim1 b-cat ub-/- Expression not detected in ureteric cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory