Tg(MSMg01-047A16)#Yuwa
Transgene Detail
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Symbol: |
Tg(MSMg01-047A16)#Yuwa |
Name: |
transgene insertion, Yuichi Wakabayashi |
MGI ID: |
MGI:6192650 |
Synonyms: |
PthMSM-Tg, Tg(047A16) |
Transgene: |
Tg(MSMg01-047A16)#Yuwa Location: unknown
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Alliance: |
Tg(MSMg01-047A16)#Yuwa page
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Transgene Type: |
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Transgenic (Inserted expressed sequence) |
Mutation: |
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Insertion
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Tg(MSMg01-047A16)#Yuwa expresses
3 genes
Transgene expresses:
Organism |
Expressed Gene |
Note |
mouse |
Bmal1 (MGI:1096381) |
BAC from Mus musculus molossinus |
mouse |
Btbd10 (MGI:1916065) |
BAC from Mus musculus molossinus |
mouse |
Pth (MGI:97799) |
BAC from Mus musculus molossinus |
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Mutation details: Mus musculus molossinus BAC clone MSMg01-047A16 (175.6 kb long; from the Riken BioResource Resaerch Center) was microinjected into the pronuclei of fertilized FVB/N oocytes. This BAC contains gene Pth and upstream sequence that includes the Btbd10 and Arntl genes. The molossinus allele of Pth contains a p.Val28Met substitution (compared to FVB/N) that confers a level of protection against skin carcinogenesis to mice carying this (trans)gene.
(J:255758)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:255758 Okumura K, et al., The parathyroid hormone regulates skin tumour susceptibility in mice. Sci Rep. 2017 Sep 11;7(1):11208 |
All: |
1 reference(s) |
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