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Tg(MSMg01-047A16)#Yuwa
Transgene Detail
Summary
Symbol: Tg(MSMg01-047A16)#Yuwa
Name: transgene insertion, Yuichi Wakabayashi
MGI ID: MGI:6192650
Synonyms: PthMSM-Tg, Tg(047A16)
Transgene: Tg(MSMg01-047A16)#Yuwa  Location: unknown  
Alliance: Tg(MSMg01-047A16)#Yuwa page
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(MSMg01-047A16)#Yuwa expresses 3 genes
 
Mutation detailsMus musculus molossinus BAC clone MSMg01-047A16 (175.6 kb long; from the Riken BioResource Resaerch Center) was microinjected into the pronuclei of fertilized FVB/N oocytes. This BAC contains gene Pth and upstream sequence that includes the Btbd10 and Arntl genes. The molossinus allele of Pth contains a p.Val28Met substitution (compared to FVB/N) that confers a level of protection against skin carcinogenesis to mice carying this (trans)gene. (J:255758)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:255758 Okumura K, et al., The parathyroid hormone regulates skin tumour susceptibility in mice. Sci Rep. 2017 Sep 11;7(1):11208
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory