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Gene Expression Data
Assay Details
Assay
Reference: J:132608 Waimey KE, et al., Plexin-A3 and plexin-A4 restrict the migration of sympathetic neurons but not their neural crest precursors. Dev Biol. 2008 Mar 15;315(2):448-58
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6191714
Gene symbol: Th
Gene name: tyrosine hydroxylase
Antibody: anti-TH
Detection system: horseradish peroxidase
Results
Specimen 1B: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: inferior cervical ganglion Present 1B
TS21: superior cervical ganglion Present 1B
TS21: sympathetic ganglion Present Regionally restricted 1B Expression in sympathetic chain ganglia.

Specimen 1C: embryonic day 13.5; Plxna3tm1Matl/Plxna3tm1Matl (more )
Structure Level Pattern Image Note
TS21: sympathetic ganglion Present Regionally restricted 1C Authors report no obvious defects in Plxna3 mutant compared with wild-type embryos.
TS21: sympathetic nervous system Present Regionally restricted 1C Authors report no obvious defects in Plxna3 mutant compared with wild-type embryos.

Specimen 1D: embryonic day 13.5; Plxna4tm1Matl/Plxna4tm1Matl (more )
Structure Level Pattern Image Note
TS21: sympathetic nervous system Present Regionally restricted 1D

Specimen 1E: embryonic day 13.5; Plxna3tm1Matl/Plxna3tm1Matl, Plxna4tm1Matl/Plxna4tm1Matl (more )
Structure Level Pattern Image Note
TS21: sympathetic nervous system Present Regionally restricted 1E Authors report abnormally located axons and cell aggregates medial to the normal ganglia.

Specimen 1F: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: sympathetic ganglion Present 1F

Specimen 1G: embryonic day 11.5; Plxna3tm1Matl/Plxna3tm1Matl, Plxna4tm1Matl/Plxna4tm1Matl (more )
Structure Level Pattern Image Note
TS19: sympathetic ganglion Present Regionally restricted 1G Authors report defects as early as E11.5.

Specimen 1H: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: sympathetic ganglion Present 1H

Specimen 1I: embryonic day 15.5; Plxna3tm1Matl/Plxna3tm1Matl, Plxna4tm1Matl/Plxna4tm1Matl (more )
Structure Level Pattern Image Note
TS23: sympathetic ganglion Present Regionally restricted 1I Authors report sympathetic defects at E15.5.

Specimen 1J: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: sympathetic ganglion Present 1J

Specimen 1K: postnatal day 1; Plxna3tm1Matl/Plxna3tm1Matl, Plxna4tm1Matl/Plxna4tm1Matl (more )
Structure Level Pattern Image Note
TS27: sympathetic ganglion Present Regionally restricted 1K Authors report defects are still apparent at postnatal day 1.

Specimen 5J: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: sympathetic nervous system Present 5J

Specimen 5K: embryonic day 13.5; Nrp2tm1Ddg/Nrp2tm1Ddg (more )
Structure Level Pattern Image Note
TS21: sympathetic nervous system Present 5K Authors report no obvious defects in Npn2 mutant.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory