Tg(Myh6-AGTR1)27Nemr
Transgene Detail
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| Symbol: |
Tg(Myh6-AGTR1)27Nemr |
| Name: |
transgene insertion 27, Mona Nemer |
| MGI ID: |
MGI:6189591 |
| Synonyms: |
alphaMHC-AT1R Tg 27 |
| Transgene: |
Tg(Myh6-AGTR1)27Nemr Location: unknown
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| Alliance: |
Tg(Myh6-AGTR1)27Nemr page
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| Strain of Origin: |
C3H x C57BL/6
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| Transgene Type: |
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Transgenic (Humanized sequence, Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(Myh6-AGTR1)27Nemr expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
AGTR1 (185) |
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mouse promoter and human gene |
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Mutation details: The transgene comprises the mouse promoter (including the last exon of the Myh7 and the first three exons of the Myh6 gene), the single coding exon of the human angiotensin II receptor type 1 gene and SV40 poly(A) signal. The mouse promoter drives expression of the human gene in the myocardium.
(J:59935)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:59935 Paradis P, et al., Overexpression of angiotensin II type I receptor in cardiomyocytes induces cardiac hypertrophy and remodeling. Proc Natl Acad Sci U S A. 2000 Jan 18;97(2):931-6 |
| All: |
1 reference(s) |
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Analysis Tools
