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Gene Expression Data
Assay Details
Assay
Reference: J:170337 Pospichalova V, et al., Generation of two modified mouse alleles of the Hic1 tumor suppressor gene. Genesis. 2011 Mar;49(3):142-51
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6188991
Gene symbol: Hic1
Gene name: hypermethylated in cancer 1
Reporter: YFP
Antibody: anti-citrine
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 3j: embryonic day 11.5; Hic1tm2.1Kori/Hic1+ (more )
Structure Level Pattern Image Note
TS19: embryo mesenchyme Present Regionally restricted 3j Expression is in mesenchyme adjacent to cartliage condensations.

Specimen 3k: embryonic day 11.5; Hic1tm2.1Kori/Hic1+ (more )
Structure Level Pattern Image Note
TS19: nasal mesenchyme Present Regionally restricted 3k Expression is in mesenchyme surrounding the nasal cavity.

Specimen 3l: embryonic day 11.5; Hic1tm2.1Kori/Hic1+ (more )
Structure Level Pattern Image Note
TS19: 1st branchial arch Present Regionally restricted 3l Expression is in mesenchyme adjacent to cartliage condensations.
TS19: tongue mesenchyme Present Regionally restricted 3l Expression is in the tongue muscle.

Specimen 3m: embryonic day 11.5; Hic1tm2.1Kori/Hic1+ (more )
Structure Level Pattern Image Note
TS19: embryo mesenchyme Present Regionally restricted 3n , 3m Expression is in mesenchyme adjacent to cartliage condensations and surrounding the spinal cord, spinal, and peripheral nerves.

Specimen 3o: embryonic day 11.5; Hic1tm2.1Kori/Hic1+ (more )
Structure Level Pattern Image Note
TS19: pancreas primordium Strong 3o

Specimen 3p: embryonic day 11.5; Hic1tm2.1Kori/Hic1+ (more )
Structure Level Pattern Image Note
TS19: gut mesenchyme Present Regionally restricted 3p Expression is facing the gut epithelium.

Specimen 3q: embryonic day 11.5; Hic1tm2.1Kori/Hic1+ (more )
Structure Level Pattern Image Note
TS19: embryo mesenchyme Present Regionally restricted 3q Expression is in mesenchyme adjacent to cartliage condensations.

Specimen 3s: embryonic day 11.5; Hic1tm2.1Kori/Hic1+ (more )
Structure Level Pattern Image Note
TS19: embryo mesenchyme Present Regionally restricted 3s , 3t Expression is in mesenchyme surrounding the spinal cord, spinal, and peripheral nerves.

Specimen 3u: embryonic day 12.5; Hic1tm2.1Kori/Hic1+ (more )
Structure Level Pattern Image Note
TS20: oral region mesenchyme Present Regionally restricted 3u Expression is in mesenchyme surrounding the salivary glands.

Specimen 3v: embryonic day 13.5; Hic1tm2.1Kori/Hic1+ (more )
Structure Level Pattern Image Note
TS21: eyelid mesenchyme Present Regionally restricted 3v Expression is in the muscle.
TS21: trigeminal ganglion Present 3v

Specimen 3w: embryonic day 13.5; Hic1tm2.1Kori/Hic1+ (more )
Structure Level Pattern Image Note
TS21: mandible Present Regionally restricted 3w Expression is in mesenchyme adjacent to cartliage condensations.
TS21: tongue muscle Present 3x , 3w

Specimen 3y: embryonic day 13.5; Hic1tm2.1Kori/Hic1+ (more )
Structure Level Pattern Image Note
TS21: embryo mesenchyme Present Regionally restricted 3y Expression is in mesenchyme adjacent to cartliage condensations.

Specimen 3z: embryonic day 13.5; Hic1tm2.1Kori/Hic1+ (more )
Structure Level Pattern Image Note
TS21: limb mesenchyme Present Regionally restricted 3z Expression is in mesenchyme adjacent to cartliage condensations and surrounding the spinal cord, spinal, and peripheral nerves.

Specimen 3aa: embryonic day 13.5; Hic1tm2.1Kori/Hic1+ (more )
Structure Level Pattern Image Note
TS21: metanephros Present 3aa

Specimen 4f: embryonic day 13.5; Hic1tm2.1Kori/Hic1+ (more )
Structure Level Pattern Image Note
TS28: placenta Present 4f
TS21: spongiotrophoblast Strong Single cells 4f
TS21: trophoblast giant cell Strong Single cells 4f
TS21: trophectoderm Strong Single cells 4f Expression is in glycogen trophoblast cells.

Specimen 4g: embryonic day 14.5; Hic1tm2.1Kori/Hic1+ (more )
Structure Level Pattern Image Note
TS28: placenta Present 4g
TS22: spongiotrophoblast Strong Single cells 4g
TS22: trophoblast giant cell Strong Single cells 4g

Specimen 4h: embryonic day 14.5; Hic1tm2.1Kori/Hic1+ (more )
Structure Level Pattern Image Note
TS28: placenta Present 4h
TS22: spongiotrophoblast Strong Single cells 4h

Specimen 4i: embryonic day 18.5; Hic1tm2.1Kori/Hic1+ (more )
Structure Level Pattern Image Note
TS28: placenta Present 4i
TS26: trophoblast giant cell Strong Single cells 4i
TS26: trophectoderm Strong Single cells 4i Expression is in glycogen trophoblast cells.

Specimen 4j: embryonic day 18.5; Hic1tm2.1Kori/Hic1+ (more )
Structure Level Pattern Image Note
TS28: placenta Present 4j
TS26: spongiotrophoblast Strong Single cells 4j
TS26: trophoblast giant cell Strong Single cells 4j


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory