Gene Expression Data
Assay Details
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Assay
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Reference:
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J:130823
Mitsiadis TA, et al., Deletion of the Pitx1 genomic locus affects mandibular tooth morphogenesis and expression of the Barx1 and Tbx1 genes. Dev Biol. 2008 Jan 15;313(2):887-96
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:6188913
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Gene symbol:
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Barx1
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Gene name:
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BarH-like homeobox 1
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Results
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Specimen
6A:
embryonic day 18.0
(more  )
Note: Double labeled: violet - Barx1; red - Pitx2 (assay MGI:6188911).
Specimen
6A:
(close  )
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Genetic Background:
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Swiss
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Age:
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embryonic day 18.0
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Note:
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Double labeled: violet - Barx1; red - Pitx2 (assay MGI:6188911).
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Specimen
6B:
embryonic day 18.0
(more )
Note: Double labeled: violet - Barx1; red - Pitx2 (assay MGI:6188911).
Specimen
6B:
(close )
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Genetic Background:
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Swiss
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Age:
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embryonic day 18.0
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Note:
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Double labeled: violet - Barx1; red - Pitx2 (assay MGI:6188911).
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Specimen
6E:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * BALB/c
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Mutant Allele(s):
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Pitx1tm1Jdr/Pitx1tm1Jdr
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Age:
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embryonic day 18.0
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
6F:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * BALB/c
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Mutant Allele(s):
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Pitx1tm1Jdr/Pitx1tm1Jdr
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Age:
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embryonic day 18.0
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: lower jaw molar dental papilla |
Weak |
Regionally restricted |
6F
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Expression decreased in mesenchyme of mandibular molars compared with maxillary molars. Weak expression in dental papilla mesenchyme of mandibular first molar.
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Specimen
7E:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * BALB/c
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Mutant Allele(s):
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Pitx1tm1Jdr/Pitx1tm1Jdr
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Age:
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embryonic day 18.0
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: molar mesenchyme |
Present |
Regionally restricted |
7E
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Expression localized to mesenchyme of developing first and second molars. Authors state intensity of expression is not identical for teeth of mandible and maxilla.
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Specimen
7F:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * BALB/c
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Mutant Allele(s):
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Pitx1tm1Jdr/Pitx1tm1Jdr
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Age:
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embryonic day 18.0
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
7G:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * BALB/c
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Mutant Allele(s):
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Pitx1tm1Jdr/Pitx1tm1Jdr
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Age:
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embryonic day 18.0
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
7H:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * BALB/c
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Mutant Allele(s):
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Pitx1tm1Jdr/Pitx1tm1Jdr
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Age:
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embryonic day 18.0
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: lower jaw molar mesenchyme |
Weak |
Regionally restricted |
7H
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Dramatically decreased expression in mesenchyme of first and second mandibular molars.
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Specimen
8A:
embryonic day 11.0
(more )
Specimen
8A:
(close )
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Genetic Background:
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Swiss
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Age:
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embryonic day 11.0
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Specimen
8B:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * BALB/c
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Mutant Allele(s):
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Pitx1tm1Jdr/Pitx1tm1Jdr
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Age:
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embryonic day 11.0
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Specimen
8C:
embryonic day 11.0
(more )
Specimen
8C:
(close )
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Genetic Background:
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Swiss
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Age:
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embryonic day 11.0
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Specimen
8D:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * BALB/c
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Mutant Allele(s):
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Pitx1tm1Jdr/Pitx1tm1Jdr
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Age:
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embryonic day 11.0
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Specimen
8E:
embryonic day 13.0
(more )
Specimen
8E:
(close )
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Genetic Background:
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Swiss
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Age:
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embryonic day 13.0
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: lower jaw |
Present |
Regionally restricted |
8E
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Expression in mandibular process.
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Specimen
8F:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * BALB/c
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Mutant Allele(s):
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Pitx1tm1Jdr/Pitx1tm1Jdr
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Age:
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embryonic day 13.0
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: lower jaw |
Ambiguous |
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8F
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Authors state expression clearly downregulated in jaw of E12.5 mutant embryo.
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Specimen
8G:
embryonic day 13.0
(more )
Specimen
8G:
(close )
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Genetic Background:
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Swiss
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Age:
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embryonic day 13.0
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: lower jaw |
Present |
Regionally restricted |
8G
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Expression in molar region of jaw.
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Specimen
8H:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * BALB/c
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Mutant Allele(s):
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Pitx1tm1Jdr/Pitx1tm1Jdr
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Age:
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embryonic day 13.0
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: lower jaw |
Ambiguous |
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8H
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Authors state expression clearly downregulated in jaw of E12.5 mutant embryo.
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Analysis Tools