Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Svep1tm1.1Ksek
Name:	sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1; targeted mutation 1.1, Kiyotoshi Sekiguchi
MGI ID:	MGI:6188639
Synonyms:	Polydom-
Gene:	Svep1  Location: Chr4:58042796-58206596 bp, - strand  Genetic Position: Chr4, 31.87 cM, cytoband B-C2
Alliance:	Svep1tm1.1Ksek page

Germline Transmission:	Earliest citation of germline transmission: J:262023
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	C57BL/6N

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A loxP site was inserted into intron 1 and an FRT site flanked neomycin resistance gene cassette and a second loxP site into intron 2. Exon 2 and the neo cassette were deleted through subsequent cre-mediated recombination. (J:262023)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Svep1 Mutation:	169 strains or lines available

Original:	J:262023 Morooka N, et al., Polydom Is an Extracellular Matrix Protein Involved in Lymphatic Vessel Remodeling. Circ Res. 2017 Apr 14;120(8):1276-1288
All:	2 reference(s)