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Tg(Cryd1/Cryaa-Sfrp2)1Jmca
Transgene Detail
Summary
Symbol: Tg(Cryd1/Cryaa-Sfrp2)1Jmca
Name: transgene insertion 1, John McAvoy
MGI ID: MGI:6187927
Synonyms: Sfrp2 lens (M2)
Transgene: Tg(Cryd1/Cryaa-Sfrp2)1Jmca  Location: unknown  
Alliance: Tg(Cryd1/Cryaa-Sfrp2)1Jmca page
Transgene
origin
Strain of Origin:  (C57BL/6 x CBA)F1
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation details: A full length mouse Sfrp2 cDNA is expressed under the control of a hybrid modified mouse A-crystallin promoter (Cryaa) and the chick delta1-crystallin (Cryd1) enhancer element. Two transgenic lines were generated, Sfrp2-m1 and Sfrp2-m2; this record referes to line m2. (J:143322)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:143322 Chen Y, et al., Wnt signaling is required for organization of the lens fiber cell cytoskeleton and development of lens three-dimensional architecture. Dev Biol. 2008 Dec 1;324(1):161-76
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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03/18/2025
MGI 6.24 		The Jackson Laboratory