Gene Expression Data
Assay Details
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Assay
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Reference:
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J:216507
Chervenak AP, et al., The role of Zic genes in inner ear development in the mouse: Exploring mutant mouse phenotypes. Dev Dyn. 2014 Nov;243(11):1487-98
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:6187913
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Gene symbol:
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Tbx1
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Gene name:
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T-box 1
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Probe:
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Tbx1 cDNA7
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Results
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Specimen
not shown E9.5 Zic2+/+:
embryonic day 9.5
(more  )
Specimen
not shown E9.5 Zic2<+/+>:
(close  )
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Genetic Background:
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129/SvEv
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: inner ear epithelium |
Present |
Regionally restricted |
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Expression was detected in the dorso-lateral half of the otic epithelium.
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| TS15: head mesenchyme |
Present |
Regionally restricted |
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Expression was detected in the mesenchyme between the neural tube and otic epithelium, as well as in the mesenchyme adjacent to the ventral otic epithelium.
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Specimen
not shown E9.5 Zic2Ku/+:
embryonic day 9.5; Zic2Ku/Zic2 +
(more )
Specimen
not shown E9.5 Zic2:
(close )
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Genetic Background:
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129S.CAnNCrl(C3)-Zic2Ku
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Mutant Allele(s):
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Zic2Ku/Zic2+
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: inner ear epithelium |
Present |
Regionally restricted |
|
Expression was detected in the dorso-lateral half of the otic epithelium.
|
| TS15: head mesenchyme |
Present |
Regionally restricted |
|
Expression was detected in the mesenchyme between the neural tube and otic epithelium, as well as in the mesenchyme adjacent to the ventral otic epithelium.
|
Specimen
not shown E9.5 Zic2Ku/Ku:
embryonic day 9.5; Zic2Ku/ Zic2Ku
(more )
Specimen
not shown E9.5 Zic2:
(close )
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Genetic Background:
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129S.CAnNCrl(C3)-Zic2Ku
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Mutant Allele(s):
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Zic2Ku/Zic2Ku
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS15: inner ear epithelium |
Present |
Regionally restricted |
|
Expression was detected in the dorso-lateral half of the otic epithelium as in wild type.
|
| TS15: head mesenchyme |
Present |
Regionally restricted |
|
Normal expression was detected in the mesenchyme between the neural tube and otic epithelium, as well as in the mesenchyme adjacent to the ventral otic epithelium.
|
Specimen
not shown E10.5 Zic2+/+:
embryonic day 10.5
(more )
Specimen
not shown E10.5 Zic2<+/+>:
(close )
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Genetic Background:
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129/SvEv
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: inner ear epithelium |
Present |
Regionally restricted |
|
Expression was detected in the dorso-lateral half of the otic epithelium.
|
| TS17: head mesenchyme |
Present |
Regionally restricted |
|
Expression was detected in the mesenchyme between the neural tube and otic epithelium, as well as in the mesenchyme adjacent to the ventral otic epithelium.
|
Specimen
not shown E10.5 Zic2Ku/+:
embryonic day 10.5; Zic2Ku/Zic2 +
(more )
Specimen
not shown E10.5 Zic2:
(close )
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Genetic Background:
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129S.CAnNCrl(C3)-Zic2Ku
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Mutant Allele(s):
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Zic2Ku/Zic2+
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS17: inner ear epithelium |
Present |
Regionally restricted |
|
Expression was detected in the dorso-lateral half of the otic epithelium.
|
| TS17: head mesenchyme |
Present |
Regionally restricted |
|
Expression was detected in the mesenchyme between the neural tube and otic epithelium, as well as in the mesenchyme adjacent to the ventral otic epithelium.
|
Specimen
not shown E10.5 Zic2Ku/Ku:
embryonic day 10.5; Zic2Ku/ Zic2Ku
(more )
Specimen
not shown E10.5 Zic2:
(close )
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Genetic Background:
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129S.CAnNCrl(C3)-Zic2Ku
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Mutant Allele(s):
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Zic2Ku/Zic2Ku
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS17: inner ear epithelium |
Present |
Regionally restricted |
|
Expression was detected in the dorso-lateral half of the otic epithelium as in wild type.
|
| TS17: head mesenchyme |
Present |
Regionally restricted |
|
Normal expression was detected in the mesenchyme between the neural tube and otic epithelium, as well as in the mesenchyme adjacent to the ventral otic epithelium.
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Analysis Tools