Gene Expression Data
Assay Details
|
Assay
|
|
Reference:
|
J:216507
Chervenak AP, et al., The role of Zic genes in inner ear development in the mouse: Exploring mutant mouse phenotypes. Dev Dyn. 2014 Nov;243(11):1487-98
|
|
Assay type:
|
RNA in situ
|
|
MGI Accession ID:
|
MGI:6187907
|
|
Gene symbol:
|
Pax2
|
|
Gene name:
|
paired box 2
|
|
Probe:
|
Pax2 cDNA10
|
|
Probe preparation:
|
Antisense labelled with digoxigenin RNA
|
|
|
Results
|
Specimen
8A:
embryonic day 9.5
(more )
Specimen
8A:
(close )
|
Genetic Background:
|
129/SvEv
|
|
Age:
|
embryonic day 9.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
8B:
embryonic day 9.5; Zic2Ku/Zic2 +
(more )
Specimen
8B:
(close )
|
Genetic Background:
|
129S.CAnNCrl(C3)-Zic2Ku
|
|
Mutant Allele(s):
|
Zic2Ku/Zic2+
|
|
Age:
|
embryonic day 9.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
8C:
(close )
|
Genetic Background:
|
129S.CAnNCrl(C3)-Zic2Ku
|
|
Mutant Allele(s):
|
Zic2Ku/Zic2Ku
|
|
Age:
|
embryonic day 9.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS15: inner ear epithelium |
Present |
|
8C
|
Expression was relatively unchanged in the otic epithelium of mutants at E9.5 when compared to wild type and heterozygous littermates.
|
Specimen
8D:
embryonic day 10.5
(more )
Specimen
8D:
(close )
|
Genetic Background:
|
129/SvEv
|
|
Age:
|
embryonic day 10.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
8E:
embryonic day 10.5; Zic2Ku/Zic2 +
(more )
Specimen
8E:
(close )
|
Genetic Background:
|
129S.CAnNCrl(C3)-Zic2Ku
|
|
Mutant Allele(s):
|
Zic2Ku/Zic2+
|
|
Age:
|
embryonic day 10.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
8F:
(close )
|
Genetic Background:
|
129S.CAnNCrl(C3)-Zic2Ku
|
|
Mutant Allele(s):
|
Zic2Ku/Zic2Ku
|
|
Age:
|
embryonic day 10.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS17: inner ear epithelium |
Present |
|
8F
|
Expression was relatively unchanged in the otic epithelium of mutants at E10.5 when compared to wild type and heterozygous littermates.
|
Specimen
8G:
embryonic day 12.5
(more )
Specimen
8G:
(close )
|
Genetic Background:
|
129/SvEv
|
|
Age:
|
embryonic day 12.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
8H:
embryonic day 12.5; Zic2Ku/Zic2 +
(more )
Specimen
8H:
(close )
|
Genetic Background:
|
129S.CAnNCrl(C3)-Zic2Ku
|
|
Mutant Allele(s):
|
Zic2Ku/Zic2+
|
|
Age:
|
embryonic day 12.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
8I:
(close )
|
Genetic Background:
|
129S.CAnNCrl(C3)-Zic2Ku
|
|
Mutant Allele(s):
|
Zic2Ku/Zic2Ku
|
|
Age:
|
embryonic day 12.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS20: inner ear epithelium |
Weak |
|
8I
|
Expression was greatly reduced in the otic epithelium of the E12.5 mutants when compared to wild type and heterozygous littermates.
|
|