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Gene Expression Data
Assay Details
Assay
Reference: J:63706 Brownell I, et al., Forkhead Foxe3 maps to the dysgenetic lens locus and is critical in lens development and differentiation. Genesis. 2000 Jun;27(2):81-93
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6187875
Gene symbol: Cryab
Gene name: crystallin, alpha B
Antibody: alpha-crystallin antibody
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 5B: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: lens vesicle Present 5B
Specimen 5C: embryonic day 12.0; Foxe3dyl/Foxe3dyl (more )
Structure Level Pattern Image Note
TS20: lens vesicle Present 5C Same as in the wild-type.
Specimen 5D: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: lens fiber Strong 5D
TS23: lens anterior epithelium Weak 5D
Specimen 5D': embryonic day 15.0; Foxe3dyl/Foxe3dyl (more )
Structure Level Pattern Image Note
TS23: lens fiber Strong 5D' Comparable to the level seen in wild type, but lack a graded upregulation in the bow region.
TS23: lens anterior epithelium Present 5D' Increased expression compared to wild type.
Specimen 5G: postnatal day 4 (more )
Structure Level Pattern Image Note
TS28: lens fiber Present 5G
TS28: lens anterior epithelium Present 5G
Specimen 5G': postnatal day 4; Foxe3dyl/Foxe3dyl (more )
Structure Level Pattern Image Note
TS28: lens anterior epithelium Present 5G'
TS28: lens fiber Present 5G' Comparable to the level seen in wild type, but lack a graded upregulation in the bow region.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory