Acvr2a Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:257654 Memic F, et al., Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:6164685
Gene symbol:	Acvr2a
Gene name:	activin receptor IIA

Antibody:	anti-activinR2A
Detection system:	Secondary antibody

Results

Specimen 5B: embryonic day 15.5 (more

)
Note: Triple labeled: red - Acvr2a; green - Elavl3/4 (to label neurons); blue - Sox10 (to label enteric progenitors).

Structure	Level	Pattern	Image	Note
TS23: enteric nervous system	Present		5B ACVR2A	Expression is seen in neurons and progenitors.

Specimen S6 - stomach - E11-12: embryonic day 11.5,12.5 (more

)
Note: White box shows higher magnification. Triple labeled: red - Acvr2a; green - Elavl3/4 (to label neurons); blue - Sox10 (to label enteric progenitors).

Structure	Level	Pattern	Image	Note
TS20: enteric nervous system	Absent		S6_ACVR2A - stomach - E11-12
TS20: gut muscularis	Present		S6_ACVR2A - stomach - E11-12

Specimen S6 - stomach - E15-16: embryonic day 15.5,16.5 (more

)
Note: Triple labeled: red - Acvr2a; green - Elavl3/4 (to label neurons); blue - Sox10 (to label enteric progenitors).

Structure	Level	Pattern	Image	Note
TS23: enteric nervous system	Present		S6_ACVR2A - stomach - E15-16	Expression was seen in many neurons and a few progenitors.

Specimen S6 - stomach - E18-19: embryonic day 18.5,19.5 (more

)
Note: Triple labeled: red - Acvr2a; green - Elavl3/4 (to label neurons); blue - Sox10 (to label enteric progenitors).

Structure	Level	Pattern	Image	Note
TS26: enteric nervous system	Present		S6_ACVR2A - stomach - E18-19	Expression was seen in many neurons.

Specimen S6 - intestine - E11-12: embryonic day 11.5,12.5 (more

)
Note: Triple labeled: red - Acvr2a; green - Elavl3/4 (to label neurons); blue - Sox10 (to label enteric progenitors).

Structure	Level	Pattern	Image	Note
TS20: enteric nervous system	Present		S6_ACVR2A - intestine - E11-12	Expression was seen in many neurons and a few progenitors.

Specimen S6 - intestine - E15-16: embryonic day 15.5,16.5 (more

)
Note: White box shows higher magnification. Triple labeled: red - Acvr2a; green - Elavl3/4 (to label neurons); blue - Sox10 (to label enteric progenitors).

Structure	Level	Pattern	Image	Note
TS23: enteric nervous system	Present		S6_ACVR2A - intestine - E15-16	Expression was seen in many neurons and a few progenitors.

Specimen S6 - intestine - E18-19: embryonic day 18.5,19.5 (more

)
Note: Triple labeled: red - Acvr2a; green - Elavl3/4 (to label neurons); blue - Sox10 (to label enteric progenitors).

Structure	Level	Pattern	Image	Note
TS26: enteric nervous system	Present		S6_ACVR2A - intestine - E18-19	Expression was seen in many neurons.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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