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Gene Expression Data
Assay Details
Assay
Reference: J:257654 Memic F, et al., Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6164664
Gene symbol: Klf7
Gene name: Kruppel-like transcription factor 7 (ubiquitous)
Antibody: anti-Klf7
Detection system: Secondary antibody
Results
Specimen Table 3A: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: enteric nervous system Present Co-expression analysis was done with neurotransmitters and neuropeptides: TH, NPY and ChAT (in the stomach) and CGRP, Calb1, and Nos1 (in the small intestine). Co-expression was seen with Th and NPY and partial co-expression with the rest.
Specimen 3C: embryonic day 18.5 (more )
Note: Double labeled: red - Klf7; green - Th (assay MGI:6188917).
Structure Level Pattern Image Note
TS26: enteric nervous system Present 3C KLF7 Co-expression with tyrosine hydroxylase (Th) was observed in the stomach.
Specimen S3 - stomach - E11-12: embryonic day 11.5,12.5 (more )
Note: Triple labeled: red - Klf7; green - Elavl3/4 (to label neurons); blue - Sox10 or Sox2 (to label enteric progenitors).
Structure Level Pattern Image Note
TS20: enteric nervous system Present S3_KLF7 - stomach - E11-12 Expression was seen in a few neurons.
Specimen S3 - stomach - E15-16: embryonic day 15.5,16.5 (more )
Note: Triple labeled: red - Klf7; green - Elavl3/4 (to label neurons); blue - Sox10 or Sox2 (to label enteric progenitors).
Structure Level Pattern Image Note
TS23: enteric nervous system Present S3_KLF7 - stomach - E15-16 Expression was seen in many neurons.
Specimen S3 - stomach - E18-19: embryonic day 18.5,19.5 (more )
Note: Triple labeled: red - Klf7; green - Elavl3/4 (to label neurons); blue - Sox10 or Sox2 (to label enteric progenitors).
Structure Level Pattern Image Note
TS26: enteric nervous system Present S3_KLF7 - stomach - E18-19 Expression was seen in many neurons.
Specimen S3 - intestine - E11-12: embryonic day 11.5,12.5 (more )
Note: Triple labeled: red - Klf7; green - Elavl3/4 (to label neurons); blue - Sox10 or Sox2 (to label enteric progenitors).
Structure Level Pattern Image Note
TS20: enteric nervous system Present S3_KLF7 - intestine - E11-12 Expression was seen in a few neurons.
Specimen S3 - intestine - E15-16: embryonic day 15.5,16.5 (more )
Note: Triple labeled: red - Klf7; green - Elavl3/4 (to label neurons); blue - Sox10 or Sox2 (to label enteric progenitors).
Structure Level Pattern Image Note
TS23: enteric nervous system Present S3_KLF7 - intestine - E15-16 Expression was seen in many neurons.
Specimen S3 - intestine - E18-19: embryonic day 18.5,19.5 (more )
Note: Triple labeled: red - Klf7; green - Elavl3/4 (to label neurons); blue - Sox10 or Sox2 (to label enteric progenitors).
Structure Level Pattern Image Note
TS26: enteric nervous system Present S3_KLF7 - intestine - E18-19 Expression was seen in many neurons.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory