Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Appem2Adiuj
Name:	amyloid beta precursor protein; endonuclease-mediated mutation 2, MODEL-AD Center
MGI ID:	MGI:6164026
Gene:	App  Location: Chr16:84751236-84972187 bp, - strand  Genetic Position: Chr16, 46.92 cM, cytoband C3-qter
Alliance:	Appem2Adiuj page

Strain of Origin:

B6(SJL)-Apoetm1.1(APOE*4)Adiuj Trem2em1Adiuj/J

Allele Type:    Endonuclease-mediated (Not Specified) Mutation:    Intragenic deletion     CRISPR/Cas9 methodologies are used to introduce a 94bp deletion in exon 14. (J:101977)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any App Mutation:	89 strains or lines available

Original:	J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:	1 reference(s)