Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Abca7em2Adiuj
Name:	ATP-binding cassette, sub-family A member 7; endonuclease-mediated mutation 2, MODEL-AD Center
MGI ID:	MGI:6164020
Gene:	Abca7  Location: Chr10:79832328-79851406 bp, + strand  Genetic Position: Chr10, 39.72 cM
Alliance:	Abca7em2Adiuj page

Strain of Origin:

B6(SJL)-Apoetm1.1(APOE*4)Adiuj Trem2em1Adiuj/J

Allele Type:    Endonuclease-mediated (Humanized sequence) Mutations:    Insertion, Nucleotide substitutions   Mutation details: CRISPR/Cas9 genome editing methodology is used to introduce an alanine to glycine at position 1527 in exon 33. (J:101977)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Abca7 Mutation:	89 strains or lines available

Original:	J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:	1 reference(s)