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Tg(Col11a2-Cilp)453intShos
Transgene Detail
Summary
Symbol: Tg(Col11a2-Cilp)453intShos
Name: transgene insertion453int, Shoji Seki
MGI ID: MGI:6163630
Synonyms: 453CilpInt, Tg(Col11a2-Cilp)3Tt
Transgene: Tg(Col11a2-Cilp)453intShos  Location: unknown  
Alliance: Tg(Col11a2-Cilp)453intShos page
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Col11a2-Cilp)453intShos expresses 1 gene
 
Mutation detailsA fragment of mouse genomic sequence from 453 bp upstream of the transcription start site of the Col11a2 gene to 380 bp downstream (the former being promoter and the latter being 5' UTR sequence), was cloned upstream of a construct containing SV40 intronic sequence and the mouse Cilp gene with influenza virus hemagglutinin (HA) epitope sequence in-frame with the 3' end. A 2.3 kb DNA fragment representing most of the first intron of Col11a2 was inserted downstream of this. This construct was microinjected into the pronuclei of C57BL/6 fertilized eggs. (J:219126)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:219126 Seki S, et al., Cartilage intermediate layer protein promotes lumbar disc degeneration. Biochem Biophys Res Commun. 2014 Apr 18;446(4):876-81
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory