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Tg(Col11a2-lacZ)742intTimk
Transgene Detail
Summary
Symbol: Tg(Col11a2-lacZ)742intTimk
Name: transgene insertion 742int, Tomoatsu Kimura
MGI ID: MGI:6163621
Synonyms: 742LaczInt
Transgene: Tg(Col11a2-lacZ)742intTimk  Location: unknown  
Alliance: Tg(Col11a2-lacZ)742intTimk page
Transgene
origin
Strain of Origin:  (C3H x C57BL/6)F1
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Mutation detailsA fragment of mouse genomic sequence from 742 bp upstream of the transcription start site of the Col11a2 gene to 380 bp downstream (the former being promoter and the latter being 5' UTR sequence), was cloned upstream of a construct containing SV40 intronic sequence, the lacZ reporter gene and SV40 poly(A) signal. A 2.3 kb DNA fragment representing most of the first intron of Col11a2 was inserted downstream of the poly(A) signal. This construct was microinjected into the pronuclei of fertilized eggs from F1 C57BL/6 C3H hybrid mice. (J:35420)
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:35420 Tsumaki N, et al., Separable cis-regulatory elements that contribute to tissue- and site-specific alpha 2(XI) collagen gene expression in the embryonic mouse cartilage. J Cell Biol. 1996 Sep;134(6):1573-82
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory