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Batf2tm1.1Kmm
Targeted Allele Detail
Summary
Symbol: Batf2tm1.1Kmm
Name: basic leucine zipper transcription factor, ATF-like 2; targeted mutation 1.1, Kenneth Murphy
MGI ID: MGI:6162639
Gene: Batf2  Location: Chr19:6214424-6222506 bp, + strand  Genetic Position: Chr19, 4.34 cM, cytoband A
Alliance: Batf2tm1.1Kmm page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:101977
Parent Cell Line:  EDJ22 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsThe targeting vector is designed to replace exons 1-2 with, from 5' to 3', a loxP site, an FRT site, a neomycin resistance (neo) cassette in reverse orientation to the gene, a second loxP site, and a second FRT site. Cre-mediated recombination removed the neo cassette. (J:188767)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Batf2 Mutation:  15 strains or lines available
Notes
The version of this allele that contains the neomycin selection cassette, Batf2tm1Kmm, has been analyzed.
References
Original:  J:188767 Tussiwand R, et al., Compensatory dendritic cell development mediated by BATF-IRF interactions. Nature. 2012 Oct 25;490(7421):502-7
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory