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Gene Expression Data
Assay Details
Assay
Reference: J:124120 Rebustini IT, et al., Laminin alpha5 is necessary for submandibular gland epithelial morphogenesis and influences FGFR expression through beta1 integrin signaling. Dev Biol. 2007 Aug 1;308(1):15-29
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6162508
Gene symbol: Lama1
Gene name: laminin, alpha 1
Antibody: mAb 8B3
Results
Specimen 2A Lama1 WT: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: submandibular gland primordium Present Regionally restricted 2A laminin alpha1 WT Expression in subepithelial basement membranes.

Specimen 2A Lama1 Lama5-/-: embryonic day 13.0; Lama5tm1Jhm/Lama5+ (more )
Structure Level Pattern Image Note
TS21: submandibular gland primordium Present 2A laminin alpha1 -/- Authors report no increase in expression in subepithelial basement membrane.

Specimen 3A: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: submandibular gland primordium epithelium Present Regionally restricted 3A Expression over entire epithelial basement membrane, accumulating in discrete areas along ducts.

Specimen 3C: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: submandibular gland primordium epithelium Present Regionally restricted 3C Expression in epithelial basement membrane in regions of cleft formation.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory