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Gene Expression Data
Assay Details
Assay
Reference: J:65872 Georgas K, et al., Characterisation of crim1 expression in the developing mouse urogenital tract reveals a sexually dimorphic gonadal expression pattern. Dev Dyn. 2000 Dec;219(4):582-7
Assay type: RNA in situ
MGI Accession ID: MGI:6160004
Gene symbol: Crim1
Gene name: cysteine rich transmembrane BMP regulator 1
Probe: Crim1 cDNA1
Probe preparation: Antisense RNA
Assay notes: Embryos were either fresh frozen or fixed in 4% paraformaldehyde.
Results
Specimen 1J: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: early nephron Present Regionally restricted 1J Expression is in the early condensates.
TS22: comma-shaped body Present Regionally restricted 1J Expression is in the distal comma-shaped bodies.
TS22: s-shaped body Present Regionally restricted 1J Expression is in the proximal s-shaped bodies.

Specimen 1M: embryonic day 12.5 (more )
Note: Double labeled: blue - Crim1; orange - Wt1 (assay MGI:6160008).
Structure Level Pattern Image Note
TS20: early nephron Present Regionally restricted 1M Expression is in the early condensates of the nephrogenic zone and is absent in the undifferentiated mesenchyme.
TS20: mesenchyme of metanephros Present Regionally restricted 1M Expression is in the early condensates of the nephrogenic zone and is absent in the undifferentiated mesenchyme.

Specimen 1N: embryonic day 17.5 (more )
Note: Double labeled: blue - Crim1; orange - Wt1 (assay MGI:6160008).
Structure Level Pattern Image Note
TS25: comma-shaped body Present 1N Expression is in the distal comma-shaped bodies.

Specimen 1O: embryonic day 17.5 (more )
Note: Double labeled: blue - Crim1; orange - Wt1 (assay MGI:6160008).
Structure Level Pattern Image Note
TS25: s-shaped body Present Regionally restricted 1O Expression is in the proximal end of the s-shaped bodies.

Specimen 2A: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: metanephros Strong Regionally restricted 2A
TS22: trunk mesenchyme Strong Regionally restricted 2A Expression is in the intermediate mesoderm between the kidneys.
TS22: ovary Absent 2A Absent in ovary and adrenal gland.

Specimen 2B: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: seminiferous cord Strong 2B

Specimen 2C: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: ovary Absent 2C

Specimen 2D: embryonic day 17.5 (more )
Note: Double labeled: blue - Crim1; orange - Wt1 (assay MGI:6160008).
Structure Cell Type Level Pattern Image Note
TS25: seminiferous cord Strong 2D
TS25: epididymis Present 2D
TS25: Leydig cell Leydig cell Weak 2D
TS25: peritubular myoid cell peritubular myoid cell Absent 2D

Specimen 2E: embryonic day 17.5 (more )
Note: Double labeled: blue - Crim1; orange - Wt1 (assay MGI:6160008).
Structure Cell Type Level Pattern Image Note
TS25: Sertoli cell Sertoli cell Strong 2E
TS25: Leydig cell Leydig cell Weak 2E
TS25: peritubular myoid cell peritubular myoid cell Absent 2E

Specimen 2F: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: ovary Absent 2F

Specimen not shown E11.5 male: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: gonad Absent

Specimen not shown E13.5 male: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: primary sex cord Weak

Specimen not shown E14.5 male: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: mesonephric tubule of male Present

Specimen not shown E13.5 female: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: ovary Absent

Specimen not shown E17.5 female: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: ovary Absent


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory