Tg(tetO/CMV-ATP2B4,-lacZ)1Husa
Transgene Detail
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| Symbol: |
Tg(tetO/CMV-ATP2B4,-lacZ)1Husa |
| Name: |
transgene insertion 1, Mansoor Husain |
| MGI ID: |
MGI:6159127 |
| Synonyms: |
hPMCA4b |
| Transgene: |
Tg(tetO/CMV-ATP2B4,-lacZ)1Husa Location: unknown
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| Alliance: |
Tg(tetO/CMV-ATP2B4,-lacZ)1Husa page
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| Strain of Origin: |
129/SvJ
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| Transgene Type: |
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Transgenic (Inducible, Inserted expressed sequence) |
| Inducer: |
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doxycycline/tetracycline |
| Mutation: |
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Insertion
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Tg(tetO/CMV-ATP2B4,-lacZ)1Husa expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
ATP2B4 (493) |
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Mutation details: The transgenic construct contains a bidirectional CMV promoter with a tetracycline operator (tetO) site, pBiGNot1, directing expression of a b-galactosidase (lacZ) reporter followed by a b-globin polyA signal on one side and human ATP2B4 cDNA squence on the other side.
(J:128144)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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| Original: |
J:128144 Gros R, et al., Plasma membrane calcium ATPase overexpression in arterial smooth muscle increases vasomotor responsiveness and blood pressure. Circ Res. 2003 Oct 3;93(7):614-21 |
| All: |
2 reference(s) |
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Analysis Tools
