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Gene Expression Data
Assay Details
Assay
Reference: J:119175 Donner AL, et al., Sox2 and Pou2f1 interact to control lens and olfactory placode development. Dev Biol. 2007 Mar 15;303(2):784-799
Assay type: RNA in situ
MGI Accession ID: MGI:6159119
Gene symbol: Six3
Gene name: sine oculis-related homeobox 3
Probe: Six3 probe21
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen S5A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: neural retina Present S5A
TS17: lens pit Present S5A
Specimen S5B: embryonic day 10.5; Pou2f1tm1Shrp/Pou2f1tm1Shrp, Sox2tm1.1Vep/Sox2+ (more )
Structure Level Pattern Image Note
TS17: optic cup Strong S5B Expression maintained in optic vesicle
TS17: eye surface ectoderm Absent S5B Expression lost from surface ectoderm.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory