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Gene Expression Data
Assay Details
Assay
Reference: J:252127 Dong N, et al., Different expression patterns of Lin28 and Lin28b in mouse molar development. Arch Oral Biol. 2017 Oct;82:280-285
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6157297
Gene symbol: Lin28b
Gene name: lin-28 homolog B
Antibody: anti-Lin28B (16178-1-AP)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 1F: embryonic day 11.5 (more )
Note: Lamina stage of tooth development.
Structure Level Pattern Image Note
TS19: mandibular process Strong Regionally restricted 1F Expression is in the dental epithelium.
TS19: oral epithelium Strong Regionally restricted 1F Expression is in the dental epithelium.
Specimen 1G: embryonic day 13.5 (more )
Note: Bud stage of tooth development.
Structure Level Pattern Image Note
TS21: lower jaw molar Present Regionally restricted 1G Expression is in the tooth bud cells near the dental epithelium.
TS21: tooth bud Present Regionally restricted 1G
Specimen 1H: embryonic day 14.5 (more )
Note: Cap stage of tooth development.
Structure Level Pattern Image Note
TS22: lower jaw molar enamel organ Present 1H
TS22: outer enamel epithelium Present 1H
TS22: primary enamel knot Present 1H
TS22: cap stage tooth Present Regionally restricted 1H
TS22: inner enamel epithelium Absent 1H
TS22: stellate reticulum Absent 1H
Specimen 2E: embryonic day 16.5 (more )
Note: Early bell stage of tooth development.
Structure Level Pattern Image Note
TS24: lower jaw molar epithelium Present 2F , 2E
TS24: outer enamel epithelium Present 2F , 2E
TS24: stellate reticulum Present 2F , 2E
TS24: early bell stage tooth Present Regionally restricted 2E , 2F
Specimen 2G: embryonic day 18.5 (more )
Note: Late bell stage of tooth development.
Structure Level Pattern Image Note
TS26: lower jaw molar enamel organ Weak Regionally restricted 2G , 2H Expression is in the outer enamel epithelium adjacent to the dental epithelium.
TS26: outer enamel epithelium Weak Regionally restricted 2G , 2H Expression is in the outer enamel epithelium adjacent to the dental epithelium.
TS26: late bell stage tooth Weak Regionally restricted 2H , 2G
Specimen 3G: postnatal day 2 (more )
Structure Level Pattern Image Note
TS27: enamel Present 3G , 3I , 3H
TS27: lower jaw molar enamel organ Absent 3G , 3H , 3I Absent in ameloblasts.
TS27: molar dental pulp Absent 3I , 3G , 3H Absent in odontoblasts.
Specimen 3J: postnatal day 6 (more )
Structure Level Pattern Image Note
TS28: enamel Present 3L , 3K , 3J
TS28: lower jaw molar enamel organ Absent 3L , 3J , 3K Absent in ameloblasts.
TS28: molar dental pulp Absent 3L , 3J , 3K Absent in odontoblasts.
Specimen 4G: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: molar dental pulp Absent 4G , 4I , 4H
Specimen 4J: postnatal day 21 (more )
Structure Level Pattern Image Note
TS28: dentin Absent 4K , 4J , 4L
TS28: enamel Absent 4K , 4J , 4L
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
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