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Gene Expression Data
Assay Details
Assay
Reference: J:252127 Dong N, et al., Different expression patterns of Lin28 and Lin28b in mouse molar development. Arch Oral Biol. 2017 Oct;82:280-285
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6157291
Gene symbol: Lin28a
Gene name: lin-28 homolog A
Antibody: anti-Lin28 (ab46020)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 1C: embryonic day 11.5 (more )
Note: Lamina stage of tooth development.
Structure Level Pattern Image Note
TS19: mandibular process Strong Regionally restricted 1C Expression is in the dental epithelium.
TS19: oral epithelium Strong Regionally restricted 1C Expression is in the dental epithelium.

Specimen 1D: embryonic day 13.5 (more )
Note: Bud stage of tooth development.
Structure Level Pattern Image Note
TS21: enamel organ Present 1D
TS21: lower jaw molar Present 1D
TS21: lower jaw molar mesenchyme Present Regionally restricted 1D Expression is in the mesenchyme underlying the enamel organ.
TS21: tooth bud Present Regionally restricted 1D

Specimen 1E: embryonic day 14.5 (more )
Note: Cap stage of tooth development.
Structure Level Pattern Image Note
TS22: cap stage tooth Present 1E
TS22: primary enamel knot Present 1E
TS22: stellate reticulum Present 1E
TS22: lower jaw molar dental follicle Present 1E
TS22: lower jaw molar epithelium Present 1E

Specimen 2A: embryonic day 16.5 (more )
Note: Early bell stage of tooth development.
Structure Level Pattern Image Note
TS24: early bell stage tooth Present 2B , 2A
TS24: inner enamel epithelium Present 2B , 2A
TS24: lower jaw molar enamel organ Present 2B , 2A
TS24: outer enamel epithelium Present 2B , 2A
TS24: stellate reticulum Present 2B , 2A
TS24: stratum intermedium Present 2B , 2A

Specimen 2C: embryonic day 18.5 (more )
Note: Late bell stage of tooth development.
Structure Level Pattern Image Note
TS26: inner enamel epithelium Present 2C , 2D
TS26: late bell stage tooth Present 2C , 2D
TS26: lower jaw molar enamel organ Present 2C , 2D
TS26: outer enamel epithelium Present 2C , 2D
TS26: secondary enamel knot Present 2C , 2D
TS26: stratum intermedium Present 2C , 2D

Specimen 3A: postnatal day 2 (more )
Structure Level Pattern Image Note
TS27: lower jaw molar enamel organ Strong Regionally restricted 3B , 3A , 3C Expression is in the secretory and mature ameloblasts.
TS27: molar dental pulp Strong Regionally restricted 3A , 3B , 3C Expression is in odontoblasts including odontoblastic bodies and processes.
TS27: enamel Present 3A , 3B , 3C
TS27: predentin Absent 3A , 3C , 3B

Specimen 3D: postnatal day 6 (more )
Structure Level Pattern Image Note
TS28: lower jaw molar enamel organ Strong Regionally restricted 3D , 3E , 3F Expression is in the secretory and mature ameloblasts.
TS28: molar dental pulp Strong Regionally restricted 3F , 3E , 3D Expression is in odontoblasts including odontoblastic bodies and processes.
TS28: enamel Present 3F , 3E , 3D
TS28: dentin Absent 3D , 3F , 3E

Specimen 4A: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: molar dental pulp Present Regionally restricted 4B , 4C , 4A Expression is in odontoblasts including odontoblastic bodies and processes.
TS28: lower jaw molar epithelium Present Regionally restricted 4A , 4C Expression is in the reduced dental epithelium.

Specimen 4D: postnatal day 21 (more )
Structure Level Pattern Image Note
TS28: molar dental pulp Present Regionally restricted 4D , 4E , 4F Expression is in odontoblasts including odontoblastic bodies and processes and in dental pulp cells.
TS28: periodontal ligament Strong 4D
TS28: blood vessel endothelium Present 4F , 4E , 4D


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory