Nme5 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:240319 Stauber M, et al., Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse. Dev Biol. 2017 Mar 15;423(2):170-188
Assay type:	RNA in situ
MGI Accession ID:	MGI:6156847
Gene symbol:	Nme5
Gene name:	NME/NM23 family member 5

Probe:	RIKEN clone 1700019D05
Probe preparation:	Antisense labelled with digoxigenin RNA
Visualized with:	Alkaline phosphatase

Results

Specimen S2Am E14.5: embryonic day 14.5 (more

)

Structure	Level	Pattern	Image	Note
TS22: lung epithelium	Present		S2Am E14.5 lung

Specimen S2Am E16.5: embryonic day 16.5 (more

)

Structure	Level	Pattern	Image	Note
TS24: lung epithelium	Present		S2Am E16.5 lung	Expression was up-regulated during development.

Specimen S2Bm lung Foxj1+/+: embryonic day 18.5 (more

)

Structure	Level	Pattern	Image	Note
TS26: lung epithelium	Present		S2Bm E18.5 lung Foxj1+/+	Expression was up-regulated during development.

Specimen S2Bm lung Foxj1-/-: embryonic day 18.5; Foxj1^tm1Slb/Foxj1^tm1Slb (more

)

Structure	Level	Pattern	Image	Note
TS26: lung epithelium	Present		S2Bm E18.5 lung Foxj1-/-	It was not possible to unambiguously identify differences in the intensity of expression in the mutant lung epithelium.

Specimen S2Bm nasal cavity Foxj1+/+: embryonic day 18.5 (more

)

Structure	Level	Pattern	Image	Note
TS26: nasal cavity respiratory epithelium	Present		S2Bm E18.5 nasal cavity Foxj1+/+	Expression in nasal cavity epithelium was stronger than in the lung epithelium.
TS26: nasopharynx epithelium	Present		S2Bm E18.5 nasal cavity Foxj1+/+	Expression in nasal cavity epithelium was stronger than in the lung epithelium.

Specimen S2Bm nasal cavity Foxj1-/-: embryonic day 18.5; Foxj1^tm1Slb/Foxj1^tm1Slb (more

)

Structure	Level	Pattern	Image	Note
TS26: nasal cavity respiratory epithelium	Weak		S2Bm E18.5 nasal cavity Foxj1-/-	Mutant showed down-regulation in respiratory epithelia of nose.
TS26: nasopharynx epithelium	Weak		S2Bm E18.5 nasal cavity Foxj1-/-	Mutant showed down-regulation in respiratory epithelia of nose.

Specimen S2Cl Foxj1+/+: embryonic day 16.5 (more

)

Structure	Level	Pattern	Image	Note
TS24: lung epithelium	Present		S2 Cl Foxj1+/+

Specimen S2Cl Foxj1-/-: embryonic day 16.5; Foxj1^tm1Slb/Foxj1^tm1Slb (more

)

Structure	Level	Pattern	Image	Note
TS24: lung epithelium	Present		S2 Cl Foxj1-/-	No apparent down-regulation of expression was visible in the mutant.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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