Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Gad2tm1Rpa
Name:	glutamic acid decarboxylase 2; targeted mutation 1, Richard D Palmiter
MGI ID:	MGI:6156077
Synonyms:	Gad2lox
Gene:	Gad2  Location: Chr2:22512262-22583889 bp, + strand  Genetic Position: Chr2, 15.15 cM, cytoband A-B
Alliance:	Gad2tm1Rpa page

Germline Transmission:	Earliest citation of germline transmission: J:232044
Parent Cell Line:	G4 (ES Cell)
Strain of Origin:	(129S6/SvEvTac x C57BL/6NCrl)F1

Allele Type:    Targeted (Conditional ready) Mutation:    Insertion     Exon 1 was flanked by loxP site and a frt-flanked neo cassette was inserted downstream of exon 1. (J:232044)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gad2 Mutation:	60 strains or lines available

Original:	J:232044 Meng F, et al., New inducible genetic method reveals critical roles of GABA in the control of feeding and metabolism. Proc Natl Acad Sci U S A. 2016 Mar 29;113(13):3645-50
All:	1 reference(s)