About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:96531 Huber K, et al., The role of Phox2B in chromaffin cell development. Dev Biol. 2005 Mar 15;279(2):501-8
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6155728
Gene symbol: Phox2b
Gene name: paired-like homeobox 2b
Reporter: lacZ
Direct Detection
Results
Specimen 1A: embryonic day 13.5; Phox2btm1Jbr/Phox2b+ (more )
Structure Level Pattern Image Note
TS21: adrenal gland Present Regionally restricted 1A Expression in sympathoadrenal (SA) chromaffin cells intermingled with adrenal cortical cells.
TS21: sympathetic ganglion Present Regionally restricted 1A Expression in the suprarenal ganglion.
Specimen 1B: embryonic day 13.5; Phox2btm1Jbr/Phox2btm1Jbr (more )
Structure Level Pattern Image Note
TS21: adrenal gland Present Regionally restricted 1B Authors state expressing cells colonize the adrenal anlage.
TS21: sympathetic ganglion Absent 1B No expression at the site of the sympathetic suprarenal ganglion.
Specimen 1C: embryonic day 14.5; Phox2btm1Jbr/Phox2b+ (more )
Structure Level Pattern Image Note
TS22: adrenal medulla Present Regionally restricted 1C Authors state expressing cells aggregate to form a centrally located adrenal medulla.
TS22: sympathetic ganglion Present Regionally restricted 1C Expression in the suprarenal ganglion.
Specimen 1D: embryonic day 14.5; Phox2btm1Jbr/Phox2btm1Jbr (more )
Structure Level Pattern Image Note
TS22: adrenal medulla Weak Regionally restricted 1D Authors report expressing cells disintegrate and become more scarce.
TS22: sympathetic ganglion Absent 1D No expression at the site of the sympathetic suprarenal ganglion.
Specimen 1E: embryonic day 15.5; Phox2btm1Jbr/Phox2b+ (more )
Structure Level Pattern Image Note
TS23: adrenal medulla Present Regionally restricted 1E Authors state expressing cells aggregate to form a centrally located adrenal medulla.
TS23: sympathetic ganglion Present Regionally restricted 1E Expression in the suprarenal ganglion.
Specimen 1F: embryonic day 15.5; Phox2btm1Jbr/Phox2btm1Jbr (more )
Structure Level Pattern Image Note
TS23: adrenal gland Weak Regionally restricted 1F Authors report expressing cells disintegrate and become more scarce.
TS23: sympathetic ganglion Absent 1F No expression at the site of the sympathetic suprarenal ganglion.
Specimen 1G: embryonic day 16.5; Phox2btm1Jbr/Phox2b+ (more )
Structure Level Pattern Image Note
TS24: adrenal medulla Present Regionally restricted 1G Authors state expressing cells aggregate to form a centrally located adrenal medulla.
TS24: sympathetic ganglion Present Regionally restricted Expression in the suprarenal ganglion.
Specimen 1H: embryonic day 16.5; Phox2btm1Jbr/Phox2btm1Jbr (more )
Structure Level Pattern Image Note
TS24: adrenal gland Weak Scattered 1H Expressing cells scattered preferentially in the periphery of the adrenal gland.
TS24: sympathetic ganglion Absent 1H No expression at the site of the sympathetic suprarenal ganglion.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory