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Bcl11btm1.1Evr
Targeted Allele Detail
Summary
Symbol: Bcl11btm1.1Evr
Name: B cell leukemia/lymphoma 11B; targeted mutation 1.1, Ellen V Rothenberg
MGI ID: MGI:6155629
Synonyms: Bcl11bYFP
Gene: Bcl11b  Location: Chr12:107876662-107969861 bp, - strand  Genetic Position: Chr12, 59.1 cM, cytoband F1
Alliance: Bcl11btm1.1Evr page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:260615
Parent Cell Line:  v6.5 (ES Cell)
Strain of Origin:  (C57BL/6 x 129S4/SvJae)F1
Mutation
description
Allele Type:    Targeted (Reporter)
Mutation:    Insertion
 
Mutation details: IRES sequence, an H2B-mCitrine (YFP) reporter fusion gene and a loxP site flanked neomycin resistance gene cassette were inserted into the 3' UTR. Cre-mediated recombination removed the selection cassette. (J:260615)
Expression
In Mice Carrying this Mutation: 2 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bcl11b Mutation:  46 strains or lines available
References
Original:  J:260615 Kueh HY, et al., Asynchronous combinatorial action of four regulatory factors activates Bcl11b for T cell commitment. Nat Immunol. 2016 Aug;17(8):956-65
All:  8 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory