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Gene Expression Data
Assay Details
Assay
Reference: J:194961 Meadows SM, et al., Resolution of defective dorsal aortae patterning in Sema3E-deficient mice occurs via angiogenic remodeling. Dev Dyn. 2013 May;242(5):570-80
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6154964
Gene symbol: Pecam1
Gene name: platelet/endothelial cell adhesion molecule 1
Antibody: anti-PECAM
Detection system: horseradish peroxidase
Results
Specimen 2A 7S +/-: embryonic day 8.0; Sema3etm1Ddg/Sema3e+ (more )
Note: 7 somite stage embryo.
Structure Level Pattern Image Note
TS12: blood vessel Present 2_7S Sema3E+/-
TS12: dorsal aorta Present 2_7S Sema3E+/-
Specimen 2A 7S -/-: embryonic day 8.0; Sema3etm1Ddg/Sema3etm1Ddg (more )
Note: 7 somite stage embryo.
Structure Level Pattern Image Note
TS12: blood vessel Present 2_7S Sema3E-/- There are numerous highly branched and honeycomb-like vessels in this mutant.
Specimen 2A 8S +/-: embryonic day 8.25; Sema3etm1Ddg/Sema3e+ (more )
Note: 8 somite stage embryo.
Structure Level Pattern Image Note
TS13: blood vessel Present 2_8S Sema3E+/-
TS13: dorsal aorta Present 2_8S Sema3E+/-
Specimen 2A 8S -/-: embryonic day 8.25; Sema3etm1Ddg/Sema3etm1Ddg (more )
Note: 8 somite stage embryo.
Structure Level Pattern Image Note
TS13: blood vessel Present 2_8S Sema3E-/- There are numerous highly branched and honeycomb-like vessels in this mutant.
Specimen 2A 9S +/-: embryonic day 8.5; Sema3etm1Ddg/Sema3e+ (more )
Note: 9 somite stage embryo.
Structure Level Pattern Image Note
TS13: blood vessel Present 2_9S Sema3E+/-
TS13: dorsal aorta Present 2_9S Sema3E+/-
Specimen 2A 9S -/-: embryonic day 8.5; Sema3etm1Ddg/Sema3etm1Ddg (more )
Note: 9 somite stage embryo.
Structure Level Pattern Image Note
TS13: blood vessel Present 2_9S Sema3E-/- There are numerous highly branched and honeycomb-like vessels in this mutant.
Specimen 2A 10S +/-: embryonic day 8.5; Sema3etm1Ddg/Sema3e+ (more )
Note: 10 somite stage embryo.
Structure Level Pattern Image Note
TS13: blood vessel Present 2_10S Sema3E+/-
TS13: dorsal aorta Present 2_10S Sema3E+/-
Specimen 2A 10S -/-: embryonic day 8.5; Sema3etm1Ddg/Sema3etm1Ddg (more )
Note: 10 somite stage embryo.
Structure Level Pattern Image Note
TS13: blood vessel Present 2_10S Sema3E-/- There are numerous highly branched and honeycomb-like vessels in this mutant.
Specimen 2A 11S +/-: embryonic day 8.5; Sema3etm1Ddg/Sema3e+ (more )
Note: 11 somite stage embryo.
Structure Level Pattern Image Note
TS13: blood vessel Present 2_11S Sema3E+/-
TS13: dorsal aorta Present 2_11S Sema3E+/-
Specimen 2A 11S -/-: embryonic day 8.5; Sema3etm1Ddg/Sema3etm1Ddg (more )
Note: 11 somite stage embryo.
Structure Level Pattern Image Note
TS13: blood vessel Present 2_11S Sema3E-/- Expression and blood vessel appearance is the same as in wild-type embryos.
TS13: dorsal aorta Present 2_11S Sema3E-/- Expression and blood vessel appearance is the same as in wild-type embryos.
Specimen 4A: embryonic day 8.0; Sema3etm1Ddg/Sema3etm1Ddg (more )
Note: 8 somite stage embryo, anterior view.
Structure Level Pattern Image Note
TS12: dorsal aorta Present 4A Expression is in an interconnected aortic plexus.
Specimen 4B: embryonic day 8.0; Sema3etm1Ddg/Sema3etm1Ddg (more )
Note: 8 somite stage embryo, ventral view.
Structure Level Pattern Image Note
TS12: dorsal aorta Present 4B Expression is in an interconnected aortic plexus.
Specimen 4C: embryonic day 8.0; Sema3etm1Ddg/Sema3etm1Ddg (more )
Note: 8 somite stage embryo, posterior view.
Structure Level Pattern Image Note
TS12: dorsal aorta Present 4C Expression is in an interconnected aortic plexus.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/28/2026
MGI 6.24 		The Jackson Laboratory