Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Tlr7tm1.1Gbrt
Name:	toll-like receptor 7; targeted mutation 1.1, Gregory M Barton
MGI ID:	MGI:6154642
Synonyms:	Tlr7FLAG:tdTomato, TLR7TOM
Gene:	Tlr7  Location: ChrX:166087925-166113554 bp, - strand  Genetic Position: ChrX, 78.31 cM, cytoband F5
Alliance:	Tlr7tm1.1Gbrt page

Germline Transmission:	Earliest citation of germline transmission: J:258639
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	C57BL/6N

Allele Type:    Targeted (Epitope tag, Reporter) Mutation:    Insertion   Mutation details: A FLAG tag was fused to the 3' end of the gene followed by an IRES-tdTomato reporter via homologous recombination. The vector also contained a loxP-flanked neomycin selection (neo) cassette, which was removed following Cre-mediated recombination. (J:258639)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Tlr7 Mutation:	21 strains or lines available

Original:	J:258639 Roberts AW, et al., Tissue-Resident Macrophages Are Locally Programmed for Silent Clearance of Apoptotic Cells. Immunity. 2017 Nov 21;47(5):913-927.e6
All:	3 reference(s)