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Epc1tm1Hko
Targeted Allele Detail
Summary
Symbol: Epc1tm1Hko
Name: enhancer of polycomb homolog 1; targeted mutation 1, Haruhiko Koseki
MGI ID: MGI:6153935
Gene: Epc1  Location: Chr18:6435951-6516108 bp, - strand  Genetic Position: Chr18, 4.48 cM, cytoband A1
Alliance: Epc1tm1Hko page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:244731
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA PGK-Neomycin resistance cassette replaced a genomic region encompassing a part of exon 3 and exons 4 and 5. (J:244731)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Epc1 Mutation:  55 strains or lines available
References
Original:  J:244731 Dong Y, et al., EPC1/TIP60-Mediated Histone Acetylation Facilitates Spermiogenesis in Mice. Mol Cell Biol. 2017 Oct 01;37(19)
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory