Gene Expression Data
Assay Details
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Assay
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Reference:
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J:104555
Viviano BL, et al., Altered hematopoiesis in glypican-3-deficient mice results in decreased osteoclast differentiation and a delay in endochondral ossification. Dev Biol. 2005 Jun 1;282(1):152-62
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:6153853
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Gene symbol:
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Casp3
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Gene name:
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caspase 3
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Results
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Specimen
5A:
embryonic day 16.5
(more  )
Specimen
5A:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 16.5
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Sex:
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Male
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: tibia |
Present |
Regionally restricted |
5A
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Authors report normal apoptosis of hypertrophic chondrocytes most distal to the growth plate.
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Specimen
5B:
embryonic day 16.5; Gpc3tm1Snd/Y
(more )
Specimen
5B:
(close )
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Genetic Background:
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involves: 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Gpc3tm1Snd/Y
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Age:
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embryonic day 16.5
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Sex:
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Male
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: tibia |
Present |
Regionally restricted |
5B
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Authors report a much broader region of of cells undergoing apoptosis, consistent with apoptosis of hypertrophic chondrocytes persisting within the diaphysis.
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Analysis Tools
