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Gene Expression Data
Assay Details
Assay
Reference: J:100569 Sajithlal G, et al., Eya 1 acts as a critical regulator for specifying the metanephric mesenchyme. Dev Biol. 2005 Aug 15;284(2):323-36
Assay type: RNA in situ
MGI Accession ID: MGI:6153519
Gene symbol: Pax2
Gene name: paired box 2
Results
Specimen 1E: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: mesonephric tubule Strong 1E
Specimen 1J: embryonic day 10.5; Eya1tm1Rilm/Eya1tm1Rilm (more )
Structure Level Pattern Image Note
TS17: mesonephric tubule Strong 1J Authors state the development of the mesonephros appeared to be normal in the mutant.
Specimen 3G: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: metanephric mesenchyme Strong 3G
TS19: ureteric bud Strong Regionally restricted 3G Strong expression in ureteric epithelium.
Specimen 3H: embryonic day 11.5; Eya1tm1Rilm/Eya1tm1Rilm (more )
Structure Level Pattern Image Note
TS19: nephric duct Present 3H Expression in Wolffian duct - not induced for ureteric bud formation.
Specimen 4G: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: metanephric mesenchyme Present 4G
TS19: ureteric bud Present 4G
Specimen 4H: embryonic day 11.5; Eya1bor/Eya1tm1Rilm (more )
Structure Level Pattern Image Note
TS19: ureteric bud Present 4H
TS19: metanephric mesenchyme Absent 4H
Specimen 4I: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: nephrogenic cord Present Regionally restricted 4I Expression in entire nephrogenic mesoderm - including anterior nephric mesenchyme and Wolffian duct.
TS17: nephric duct Present 4I Expression in entire nephrogenic mesoderm - including anterior nephric mesenchyme and Wolffian duct.
TS17: metanephric mesenchyme Strong Regionally restricted 4I Strong expression in caudal metanephric mesenchyme.
Specimen 4J: embryonic day 10.5; Eya1bor/Eya1tm1Rilm (more )
Structure Level Pattern Image Note
TS17: nephrogenic cord Present Regionally restricted 4J Normal expression in anterior nephrogenic mesenchyme and Wolffian duct.
TS17: nephric duct Present 4J Normal expression in anterior nephrogenic mesenchyme and Wolffian duct.
TS17: metanephric mesenchyme Weak Regionally restricted 4J Markedly reduced expression in metanephric mesenchyme. Very weak expression in caudal region where ureteric bud forms.
Specimen 4K: embryonic day 10.5; Eya1tm1Rilm/Eya1tm1Rilm (more )
Structure Level Pattern Image Note
TS17: nephrogenic cord Present Regionally restricted 4K Normal expression in anterior nephrogenic mesenchyme and Wolffian duct.
TS17: nephric duct Present 4K Normal expression in anterior nephrogenic mesenchyme and Wolffian duct.
TS17: metanephric mesenchyme Absent 4K
Specimen 4L: embryonic day 10.5; Six1tm1Mair/Six1tm1Mair (more )
Structure Level Pattern Image Note
TS17: nephrogenic cord Present Regionally restricted 4L Normal expression in anterior nephrogenic mesenchyme and Wolffian duct.
TS17: nephric duct Present 4L Normal expression in anterior nephrogenic mesenchyme and Wolffian duct.
TS17: metanephric mesenchyme Weak Regionally restricted 4L Markedly reduced expression in metanephric mesenchyme.
Specimen 6K: embryonic day 11.5; Pax2tm1Pgr/Pax2tm1Pgr (more )
Structure Level Pattern Image Note
TS19: ureteric bud Present Regionally restricted 6K Authors report ureteric bud invades into mesenchyme.
Specimen 6L: embryonic day 11.5; Eya1tm1Rilm/Eya1+, Pax2tm1Pgr/Pax2+, Six1tm1Mair/Six1+ (more )
Structure Level Pattern Image Note
TS19: ureteric bud Strong Regionally restricted 6L Authors report failure of ureteric bud to branch out.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory