Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | Notes | References

Symbol:	Oxtrtm1(cre/GFP)Rpa
Name:	oxytocin receptor; targeted mutation 1, Richard D Palmiter
MGI ID:	MGI:6153224
Gene:	Oxtr  Location: Chr6:112450644-112466904 bp, - strand  Genetic Position: Chr6, 52.27 cM, cytoband E3
Alliance:	Oxtrtm1(cre/GFP)Rpa page

Germline Transmission:	Earliest citation of germline transmission: J:256724
Parent Cell Line:	G4 (ES Cell)
Strain of Origin:	(129S6/SvEvTac x C57BL/6NCrl)F1

Allele Type:    Targeted (Recombinase, Reporter) Mutation:    Insertion   Oxtrtm1(cre/GFP)Rpa expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Oxtr (MGI:109147)   Mutation details: IRES-Myc tag-nuclear localization signal (NLS)-cre-GFP-frt-neomycin-frt were introduced just after the termination codon of the mouse Oxtr gene via homologous recombination. (J:256724)

Activity:	Tissue activity of this recombinase allele
Driver:	Oxtr (mouse) Summary of all recombinase alleles driven by Oxtr. Alliance mouse Oxtr gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Oxtr Mutation:	40 strains or lines available

Original:	J:256724 Ryan PJ, et al., Oxytocin-receptor-expressing neurons in the parabrachial nucleus regulate fluid intake. Nat Neurosci. 2017 Dec;20(12):1722-1733
All:	2 reference(s)