Gene Expression Data
Assay Details
Assay
|
Reference:
|
J:249839
Vermeren M, et al., Osteoclast stimulation factor 1 (Ostf1) KNOCKOUT increases trabecular bone mass in mice. Mamm Genome. 2017 Dec;28(11-12):498-514
|
Assay type:
|
In situ reporter (knock in)
|
MGI Accession ID:
|
MGI:6152761
|
Gene symbol:
|
Ostf1
|
Gene name:
|
osteoclast stimulating factor 1
|
Reporter:
|
lacZ
|
|
Direct Detection
|
Assay notes:
|
It was not specified the samples were from the heterozgous or homozygous in most of the data.
|
|
Results
|
Specimen
2B:
(close )
Genetic Background:
|
C57BL/6-Ostf1tm1(NCOM)Cmhd
|
Mutant Allele(s):
|
Ostf1tm1(NCOM)Cmhd/Ostf1+
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Cryosection
|
Specimen
2C:
(close )
Genetic Background:
|
C57BL/6-Ostf1tm1(NCOM)Cmhd
|
Mutant Allele(s):
|
Ostf1tm1(NCOM)Cmhd/Ostf1+
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Cryosection
|
Specimen
2D:
(close )
Genetic Background:
|
C57BL/6-Ostf1tm1(NCOM)Cmhd
|
Mutant Allele(s):
|
Ostf1tm1(NCOM)Cmhd/Ostf1+
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Cryosection
|
Specimen
2E:
(close )
Genetic Background:
|
C57BL/6-Ostf1tm1(NCOM)Cmhd
|
Mutant Allele(s):
|
Ostf1tm1(NCOM)Cmhd/Ostf1+
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Cryosection
|
Specimen
2F:
(close )
Genetic Background:
|
C57BL/6-Ostf1tm1(NCOM)Cmhd
|
Mutant Allele(s):
|
Ostf1tm1(NCOM)Cmhd/Ostf1+
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Cryosection
|
Specimen
2G:
(close )
Genetic Background:
|
C57BL/6-Ostf1tm1(NCOM)Cmhd
|
Mutant Allele(s):
|
Ostf1tm1(NCOM)Cmhd/Ostf1+
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Cryosection
|
Specimen
2H:
(close )
Genetic Background:
|
C57BL/6-Ostf1tm1(NCOM)Cmhd
|
Mutant Allele(s):
|
Ostf1tm1(NCOM)Cmhd/Ostf1+
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Cryosection
|
Specimen
2I:
(close )
Genetic Background:
|
C57BL/6-Ostf1tm1(NCOM)Cmhd
|
Mutant Allele(s):
|
Ostf1tm1(NCOM)Cmhd/Ostf1+
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Cryosection
|
Specimen
2J:
(close )
Genetic Background:
|
C57BL/6-Ostf1tm1(NCOM)Cmhd
|
Mutant Allele(s):
|
Ostf1tm1(NCOM)Cmhd/Ostf1+
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Cryosection
|
Specimen
2K:
(close )
Genetic Background:
|
C57BL/6-Ostf1tm1(NCOM)Cmhd
|
Mutant Allele(s):
|
Ostf1tm1(NCOM)Cmhd/Ostf1+
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Cryosection
|
Specimen
2L:
(close )
Genetic Background:
|
C57BL/6-Ostf1tm1(NCOM)Cmhd
|
Mutant Allele(s):
|
Ostf1tm1(NCOM)Cmhd/Ostf1+
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: brain blood vessel |
Strong |
Regionally restricted |
2L
|
Expressed in the endothelium in large and small vessels.
|
TS28: meninges |
Present |
|
2L
|
Expressed in the lining of the brain, the ventricles as well as the choroid plexus.
|
Specimen
2M:
(close )
Genetic Background:
|
C57BL/6-Ostf1tm1(NCOM)Cmhd
|
Mutant Allele(s):
|
Ostf1tm1(NCOM)Cmhd/Ostf1+
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: brain blood vessel |
Strong |
Regionally restricted |
2M
|
Expressed in the endothelium in large and small vessels.
|
TS28: brain |
Present |
Regionally restricted |
2M
|
Expressed in small branched cells, presumably oligodendrocytes and their precursors, everywhere except in the cerebellum.
|
Specimen
2N:
(close )
Genetic Background:
|
C57BL/6-Ostf1tm1(NCOM)Cmhd
|
Mutant Allele(s):
|
Ostf1tm1(NCOM)Cmhd/Ostf1+
|
Age:
|
embryonic day 14.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Cryosection
|
Specimen
2O:
(close )
Genetic Background:
|
C57BL/6-Ostf1tm1(NCOM)Cmhd
|
Mutant Allele(s):
|
Ostf1tm1(NCOM)Cmhd/Ostf1+
|
Age:
|
embryonic day 14.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Cryosection
|
Specimen
2P:
(close )
Genetic Background:
|
C57BL/6-Ostf1tm1(NCOM)Cmhd
|
Mutant Allele(s):
|
Ostf1tm1(NCOM)Cmhd/Ostf1+
|
Age:
|
embryonic day 14.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Cryosection
|
Specimen
3A:
(close )
Genetic Background:
|
C57BL/6-Ostf1tm1(NCOM)Cmhd
|
Mutant Allele(s):
|
Ostf1tm1(NCOM)Cmhd/Ostf1+
|
Age:
|
embryonic day 11.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Cryosection
|
Specimen
3B:
(close )
Genetic Background:
|
C57BL/6-Ostf1tm1(NCOM)Cmhd
|
Mutant Allele(s):
|
Ostf1tm1(NCOM)Cmhd/Ostf1+
|
Age:
|
embryonic day 11.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Cryosection
|
Specimen
3C:
(close )
Genetic Background:
|
C57BL/6-Ostf1tm1(NCOM)Cmhd
|
Mutant Allele(s):
|
Ostf1tm1(NCOM)Cmhd/Ostf1+
|
Age:
|
embryonic day 11.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Cryosection
|
Specimen
3D:
(close )
Genetic Background:
|
C57BL/6-Ostf1tm1(NCOM)Cmhd
|
Mutant Allele(s):
|
Ostf1tm1(NCOM)Cmhd/Ostf1+
|
Age:
|
embryonic day 15.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Cryosection
|
Specimen
3E:
(close )
Genetic Background:
|
C57BL/6-Ostf1tm1(NCOM)Cmhd
|
Mutant Allele(s):
|
Ostf1tm1(NCOM)Cmhd/Ostf1+
|
Age:
|
embryonic day 15.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Cryosection
|
Specimen
3F:
(close )
Genetic Background:
|
C57BL/6-Ostf1tm1(NCOM)Cmhd
|
Mutant Allele(s):
|
Ostf1tm1(NCOM)Cmhd/Ostf1+
|
Age:
|
embryonic day 15.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Cryosection
|
Specimen
3G:
(close )
Genetic Background:
|
C57BL/6-Ostf1tm1(NCOM)Cmhd
|
Mutant Allele(s):
|
Ostf1tm1(NCOM)Cmhd/Ostf1+
|
Age:
|
embryonic day 15.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Cryosection
|
Specimen
3H:
(close )
Genetic Background:
|
C57BL/6-Ostf1tm1(NCOM)Cmhd
|
Mutant Allele(s):
|
Ostf1tm1(NCOM)Cmhd/Ostf1+
|
Age:
|
embryonic day 15.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Cryosection
|
Specimen
3I:
(close )
Genetic Background:
|
C57BL/6-Ostf1tm1(NCOM)Cmhd
|
Mutant Allele(s):
|
Ostf1tm1(NCOM)Cmhd/Ostf1+
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Cryosection
|
Specimen
3J:
(close )
Genetic Background:
|
C57BL/6-Ostf1tm1(NCOM)Cmhd
|
Mutant Allele(s):
|
Ostf1tm1(NCOM)Cmhd/Ostf1+
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Cryosection
|
Specimen
3K:
(close )
Genetic Background:
|
C57BL/6-Ostf1tm1(NCOM)Cmhd
|
Mutant Allele(s):
|
Ostf1tm1(NCOM)Cmhd/Ostf1+
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Cryosection
|
Specimen
3L:
(close )
Genetic Background:
|
C57BL/6-Ostf1tm1(NCOM)Cmhd
|
Mutant Allele(s):
|
Ostf1tm1(NCOM)Cmhd/Ostf1+
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Cryosection
|
Specimen
3M:
(close )
Genetic Background:
|
C57BL/6-Ostf1tm1(NCOM)Cmhd
|
Mutant Allele(s):
|
Ostf1tm1(NCOM)Cmhd/Ostf1+
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Cryosection
|
Specimen
4A:
(close )
Genetic Background:
|
C57BL/6-Ostf1tm1(NCOM)Cmhd
|
Mutant Allele(s):
|
Ostf1tm1(NCOM)Cmhd/Ostf1+
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Specimen
4B:
(close )
Genetic Background:
|
C57BL/6-Ostf1tm1(NCOM)Cmhd
|
Mutant Allele(s):
|
Ostf1tm1(NCOM)Cmhd/Ostf1+
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Specimen
4C/D:
(close )
Genetic Background:
|
C57BL/6-Ostf1tm1(NCOM)Cmhd
|
Mutant Allele(s):
|
Ostf1tm1(NCOM)Cmhd/Ostf1+
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Specimen
4E:
(close )
Genetic Background:
|
involves: C57BL/6
|
Mutant Allele(s):
|
Ostf1tm1(NCOM)Cmhd/Ostf1tm1(NCOM)Cmhd
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Cryosection
|
Note:
|
albino mouse
|
Specimen
4F:
(close )
Genetic Background:
|
C57BL/6-Ostf1tm1(NCOM)Cmhd
|
Mutant Allele(s):
|
Ostf1tm1(NCOM)Cmhd/Ostf1+
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: retina |
Present |
Regionally restricted |
4F
|
Expressed in Muller glial cells.
|
Specimen
4G:
(close )
Genetic Background:
|
C57BL/6-Ostf1tm1(NCOM)Cmhd
|
Mutant Allele(s):
|
Ostf1tm1(NCOM)Cmhd/Ostf1+
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Cryosection
|
Specimen
4I:
(close )
Genetic Background:
|
C57BL/6-Ostf1tm1(NCOM)Cmhd
|
Mutant Allele(s):
|
Ostf1tm1(NCOM)Cmhd/Ostf1+
|
Age:
|
postnatal day 6
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: eye |
Present |
Regionally restricted |
4I
|
Expressed in the capillary network.
|
Specimen
5A:
(close )
Genetic Background:
|
C57BL/6-Ostf1tm1(NCOM)Cmhd
|
Mutant Allele(s):
|
Ostf1tm1(NCOM)Cmhd/Ostf1+
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Cryosection
|
Specimen
5B:
(close )
Genetic Background:
|
C57BL/6-Ostf1tm1(NCOM)Cmhd
|
Mutant Allele(s):
|
Ostf1tm1(NCOM)Cmhd/Ostf1+
|
Age:
|
embryonic day 15.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Cryosection
|
Specimen
5C:
(close )
Genetic Background:
|
C57BL/6-Ostf1tm1(NCOM)Cmhd
|
Mutant Allele(s):
|
Ostf1tm1(NCOM)Cmhd/Ostf1+
|
Age:
|
embryonic day 15.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS23: liver parenchyma |
Strong |
Scattered |
5C
|
Expressed in distinct cells spread in the parenchyme, likely to be hematopoietic stem cells.
|
Specimen
5D:
(close )
Genetic Background:
|
C57BL/6-Ostf1tm1(NCOM)Cmhd
|
Mutant Allele(s):
|
Ostf1tm1(NCOM)Cmhd/Ostf1+
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: liver |
Present |
Graded |
5D
|
Expressed exclusively in endothelial cells in a low-to high gradient from the hepatic zone 1 surrounding the portal vein to zone 3 around the central vein.
|
Specimen
6A:
(close )
Genetic Background:
|
C57BL/6-Ostf1tm1(NCOM)Cmhd
|
Mutant Allele(s):
|
Ostf1tm1(NCOM)Cmhd/Ostf1+
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Cryosection
|
Specimen
6B:
(close )
Genetic Background:
|
C57BL/6-Ostf1tm1(NCOM)Cmhd
|
Mutant Allele(s):
|
Ostf1tm1(NCOM)Cmhd/Ostf1+
|
Age:
|
embryonic day 14.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS22: aortic valve |
Present |
Regionally restricted |
6B
|
Expressed at the surface of the lips.
|
TS22: dorsal aorta |
Present |
Regionally restricted |
6B
|
Expressed in the endothelium.
|
Specimen
6C:
(close )
Genetic Background:
|
C57BL/6-Ostf1tm1(NCOM)Cmhd
|
Mutant Allele(s):
|
Ostf1tm1(NCOM)Cmhd/Ostf1+
|
Age:
|
embryonic day 14.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Cryosection
|
Specimen
7A:
(close )
Genetic Background:
|
C57BL/6-Ostf1tm1(NCOM)Cmhd
|
Mutant Allele(s):
|
Ostf1tm1(NCOM)Cmhd/Ostf1+
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Cryosection
|
Specimen
7B:
(close )
Genetic Background:
|
C57BL/6-Ostf1tm1(NCOM)Cmhd
|
Mutant Allele(s):
|
Ostf1tm1(NCOM)Cmhd/Ostf1+
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Cryosection
|
Specimen
7C:
(close )
Genetic Background:
|
C57BL/6-Ostf1tm1(NCOM)Cmhd
|
Mutant Allele(s):
|
Ostf1tm1(NCOM)Cmhd/Ostf1+
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Cryosection
|
Specimen
7D:
(close )
Genetic Background:
|
C57BL/6-Ostf1tm1(NCOM)Cmhd
|
Mutant Allele(s):
|
Ostf1tm1(NCOM)Cmhd/Ostf1+
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Cryosection
|
Specimen
7E:
(close )
Genetic Background:
|
C57BL/6-Ostf1tm1(NCOM)Cmhd
|
Mutant Allele(s):
|
Ostf1tm1(NCOM)Cmhd/Ostf1+
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: ureter |
Present |
|
7E
|
Expressed in the ureter wall in a mosaic of high expression patches surrounded by low expression.
|
TS28: renal papilla |
Present |
|
7E
|
Highest expression.
|
Specimen
7F:
(close )
Genetic Background:
|
C57BL/6-Ostf1tm1(NCOM)Cmhd
|
Mutant Allele(s):
|
Ostf1tm1(NCOM)Cmhd/Ostf1+
|
Age:
|
postnatal day 0
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Specimen
7G:
(close )
Genetic Background:
|
C57BL/6-Ostf1tm1(NCOM)Cmhd
|
Mutant Allele(s):
|
Ostf1tm1(NCOM)Cmhd/Ostf1+
|
Age:
|
embryonic day 14.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Cryosection
|
Specimen
8A/B embryo:
(close )
Genetic Background:
|
C57BL/6-Ostf1tm1(NCOM)Cmhd
|
Mutant Allele(s):
|
Ostf1tm1(NCOM)Cmhd/Ostf1tm1(NCOM)Cmhd
|
Age:
|
embryonic day 14.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Cryosection
|
Specimen
8A/B mother:
(close )
Genetic Background:
|
C57BL/6-Ostf1tm1(NCOM)Cmhd
|
Mutant Allele(s):
|
Ostf1tm1(NCOM)Cmhd/Ostf1+
|
Age:
|
postnatal adult
|
Sex:
|
Female
|
Type:
|
section
|
Embedding:
|
Cryosection
|
Specimen
8C:
(close )
Genetic Background:
|
C57BL/6-Ostf1tm1(NCOM)Cmhd
|
Mutant Allele(s):
|
Ostf1tm1(NCOM)Cmhd/Ostf1+
|
Age:
|
embryonic day 14.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Cryosection
|
Specimen
not shown:
(close )
Genetic Background:
|
C57BL/6-Ostf1tm1(NCOM)Cmhd
|
Mutant Allele(s):
|
Ostf1tm1(NCOM)Cmhd/Ostf1+
|
Age:
|
embryonic day 14.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Cryosection
|
Specimen
not shown:
(close )
Genetic Background:
|
C57BL/6-Ostf1tm1(NCOM)Cmhd
|
Mutant Allele(s):
|
Ostf1tm1(NCOM)Cmhd/Ostf1+
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Cryosection
|
Specimen
not shown:
postnatal adult; Ostf1tm1(NCOM)Cmhd/Ostf1 +
(more )
Note: Summarized in Table 1.
Specimen
not shown:
(close )
Genetic Background:
|
C57BL/6-Ostf1tm1(NCOM)Cmhd
|
Mutant Allele(s):
|
Ostf1tm1(NCOM)Cmhd/Ostf1+
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Embedding:
|
Cryosection
|
Note:
|
Summarized in Table 1.
|
|