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Gene Expression Data
Assay Details
Assay
Reference: J:222431 Cunningham TJ, et al., Wnt8a and Wnt3a cooperate in the axial stem cell niche to promote mammalian body axis extension. Dev Dyn. 2015 Jun;244(6):797-807
Assay type: RNA in situ
MGI Accession ID: MGI:6151388
Gene symbol: Wnt8a
Gene name: wingless-type MMTV integration site family, member 8A
Probe: Wnt8a cDNA5
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1A 5s top: embryonic day 8.0 (more )
Note: 5 somite stage embryo.
Structure Level Pattern Image Note
TS12: future hindbrain Present 1A 5 somites top
TS12: embryo Present Regionally restricted 1A 5 somites top Expression is in the anterior two-thirds of the epiblast.
Specimen 1A 5s bottom: embryonic day 8.0 (more )
Note: 5 somite stage embryo.
Structure Level Pattern Image Note
TS12: future hindbrain Present 1A 5 somites bottom
TS12: embryo Present Regionally restricted 1A 5 somites bottom Expression is in the anterior two-thirds of the epiblast.
Specimen 1A 7s top: embryonic day 8.0 (more )
Note: 7 somite stage embryo.
Structure Level Pattern Image Note
TS12: future hindbrain Present 1A 7 somites top
TS12: embryo Present Regionally restricted 1A 7 somites top Expression is in the anterior two-thirds of the epiblast.
Specimen 1A 7s bottom: embryonic day 8.0 (more )
Note: 7 somite stage embryo.
Structure Level Pattern Image Note
TS12: future hindbrain Present 1A 7 somites bottom
TS12: embryo Present Regionally restricted 1A 7 somites bottom Expression is in the anterior two-thirds of the epiblast.
Specimen 1A 10s top: embryonic day 8.5 (more )
Note: 10 somite stage embryo.
Structure Level Pattern Image Note
TS13: future hindbrain Weak 1A 10 somites top
Specimen 1A 10s bottom: embryonic day 8.5 (more )
Note: 10 somite stage embryo.
Structure Level Pattern Image Note
TS13: future hindbrain Weak 1A 10 somites bottom
Specimen 1A 12s top: embryonic day 8.5 (more )
Note: 12 somite stage embryo.
Structure Level Pattern Image Note
TS13: future hindbrain Absent 1A 12 somites top
Specimen 1A 12s bottom: embryonic day 8.5 (more )
Note: 12 somite stage embryo.
Structure Level Pattern Image Note
TS13: future hindbrain Absent 1A 12 somites bottom
Specimen 1B left: embryonic day 8.0; Wnt8atm1(KOMP)Vlcg/Wnt8atm1(KOMP)Vlcg (more )
Note: 7 somite stage embryo.
Structure Level Pattern Image Note
TS12: embryo Absent 1B left
Specimen 1B right: embryonic day 8.0; Wnt8atm1(KOMP)Vlcg/Wnt8atm1(KOMP)Vlcg (more )
Note: 7 somite stage embryo.
Structure Level Pattern Image Note
TS12: embryo Absent 1B right
Specimen 5A WT left: embryonic day 8.0 (more )
Note: 7 somite stage embryo.
Structure Level Pattern Image Note
TS12: future hindbrain Present 5A WT left
TS12: embryo Present Regionally restricted 5A WT left Expression is in a caudal domain.
Specimen 5A WT right: embryonic day 8.0 (more )
Note: 7 somite stage embryo.
Structure Level Pattern Image Note
TS12: future hindbrain Present 5A WT right
TS12: embryo Present Regionally restricted 5A WT right Expression is in a caudal domain.
Specimen 5A Rdh10-/- left: embryonic day 8.0; Rdh10tm1d(KOMP)Wtsi/Rdh10tm1d(KOMP)Wtsi (more )
Note: 7 somite stage embryo.
Structure Level Pattern Image Note
TS12: future hindbrain Present 5A Rdh10-/- left
TS12: embryo Present Regionally restricted 5A Rdh10-/- left The caudal expression domain has expanded in this mutant.
Specimen 5A Rdh10-/- right: embryonic day 8.0; Rdh10tm1d(KOMP)Wtsi/Rdh10tm1d(KOMP)Wtsi (more )
Note: 7 somite stage embryo.
Structure Level Pattern Image Note
TS12: future hindbrain Present 5A Rdh10-/- right
TS12: embryo Present Regionally restricted 5A Rdh10-/- right The caudal expression domain has expanded in this mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory