Tg(tetO-Notch1*)1Dam
Transgene Detail
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| Symbol: |
Tg(tetO-Notch1*)1Dam |
| Name: |
transgene insertion 1, Douglas A Melton |
| MGI ID: |
MGI:6151073 |
| Synonyms: |
tetO-NICD, tet-on-NICD, tetO-NotchIC |
| Transgene: |
Tg(tetO-Notch1*)1Dam Location: unknown
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| Alliance: |
Tg(tetO-Notch1*)1Dam page
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| Strain of Origin: |
B6CBAF1
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| Transgene Type: |
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Transgenic (Inducible, Inserted expressed sequence) |
| Inducer: |
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doxycycline/tetracycline |
| Mutation: |
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Insertion
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Tg(tetO-Notch1*)1Dam expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Note |
| mouse |
Notch1 (MGI:97363) |
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Mutation details: The intracellular portion of mouse Notch1 (amino acids 1749-2293) is placed downstream of a tet operon; the protein domain is expressed under the control of inducible tetracycline transactivator elements.
(J:101154)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:101154 Stanger BZ, et al., Direct regulation of intestinal fate by Notch. Proc Natl Acad Sci U S A. 2005 Aug 30;102(35):12443-8 |
| All: |
10 reference(s) |
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Analysis Tools
