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Gene Expression Data
Assay Details
Assay
Reference: J:143350 Bohm J, et al., Sall1, sall2, and sall4 are required for neural tube closure in mice. Am J Pathol. 2008 Nov;173(5):1455-63
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6150838
Gene symbol: Casp3
Gene name: caspase 3
Antibody: anti-activated Caspase 3 (AF835)
Detection system: Biotinylated secondary antibody/[Strept]avidin
Assay notes: Fixative was Serra: ethanol:37% formaldehyde:acetic acid, 6:3:1.
Results
Specimen 4F: embryonic day 8.5 (more )
Note: 9 somites.
Structure Level Pattern Image Note
TS13: embryo Present Single cells 4F Expression is in cells close to the bending of the neural tube.

Specimen 4G: embryonic day 8.5; Sall2tm1Jkoh/Sall2tm1Jkoh, Sall4Gt(W097E01)Flo/Sall4+ (more )
Note: 9 somites.
Structure Level Pattern Image Note
TS13: embryo Present Single cells 4G The number of positive cells was increased in this mutant.

Specimen 4H: embryonic day 8.5 (more )
Note: 12 somites.
Structure Level Pattern Image Note
TS13: embryo Present Single cells 4H Expression is in cells close to the bending of the neural tube.

Specimen 4I: embryonic day 8.5; Sall2tm1Jkoh/Sall2tm1Jkoh, Sall4Gt(W097E01)Flo/Sall4+ (more )
Note: 12 somites.
Structure Level Pattern Image Note
TS13: embryo Present Single cells 4I The number of positive cells was increased in this mutant.

Specimen 4J: embryonic day 9.0 (more )
Note: 14 somites.
Structure Level Pattern Image Note
TS14: embryo Present Single cells 4J Expression is in cells close to the bending of the neural tube.

Specimen 4K: embryonic day 9.0; Sall2tm1Jkoh/Sall2tm1Jkoh, Sall4Gt(W097E01)Flo/Sall4+ (more )
Note: 14 somites.
Structure Level Pattern Image Note
TS14: embryo Present Single cells 4K The number of positive cells was increased in this mutant.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/31/2026
MGI 6.24
The Jackson Laboratory