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Tg(MVV-MPO)7027Rcl
Transgene Detail
Summary
Symbol: Tg(MVV-MPO)7027Rcl
Name: transgene insertion 7027, Renee LeBoeuf
MGI ID: MGI:6150816
Synonyms: MPO-Tg
Transgene: Tg(MVV-MPO)7027Rcl  Location: unknown  
Alliance: Tg(MVV-MPO)7027Rcl page
Transgene
origin
Strain of Origin:  C57BL/6J
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(MVV-MPO)7027Rcl expresses 1 gene
 
Mutation detailsThe transgene was designed with cDNA from the human MPO (myeloperoxidase) gene under the control of the Visna virus LTR promoter. Western blot confirms expression of MPO protein in macrophages. (J:112270)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:112270 McMillen TS, et al., Expression of human myeloperoxidase by macrophages promotes atherosclerosis in mice. Circulation. 2005 May 31;111(21):2798-804
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory