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Gene Expression Data
Assay Details
Assay
Reference: J:249970 Furtado MB, et al., Mutations in the Katnb1 gene cause left-right asymmetry and heart defects. Dev Dyn. 2017 Dec;246(12):1027-1035
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6150455
Gene symbol: Katnb1
Gene name: katanin p80 (WD40-containing) subunit B 1
Reporter: lacZ
Direct Detection
Results
Specimen 1A: embryonic day 6.5; Katnb1tm1a(EUCOMM)Hmgu/Katnb1+ (more )
Structure Level Pattern Image Note
TS9: embryo Present Ubiquitous 1A
TS9: primitive streak Present 1A Enriched expression was found in the gastrulating nodal tissue and primitive streak.

Specimen 1B: embryonic day 7.5; Katnb1tm1a(EUCOMM)Hmgu/Katnb1+ (more )
Structure Level Pattern Image Note
TS11: node Strong Regionally restricted 1B' , 1B Expressed in the node pit and crown cells.
TS11: cardiogenic plate Weak 1B cardiac crescent region

Specimen 1C: embryonic day 7.5; Katnb1tm1a(EUCOMM)Hmgu/Katnb1+ (more )
Structure Level Pattern Image Note
TS11: node Strong Regionally restricted 1C Expressed in the node crown cells.

Specimen 1D: embryonic day 7.5; Katnb1tm1a(EUCOMM)Hmgu/Katnb1+ (more )
Structure Level Pattern Image Note
TS11: node Strong Regionally restricted 1D Expressed in the node pit.

Specimen 1E: embryonic day 8.5; Katnb1tm1a(EUCOMM)Hmgu/Katnb1+ (more )
Structure Level Pattern Image Note
TS13: node Present 1E" , 1E
TS13: embryo Present Regionally restricted 1E' , 1E Expressed in the midline.

Specimen 1F right: embryonic day 8.5; Katnb1tm1a(EUCOMM)Hmgu/Katnb1+ (more )
Note: stained for longer periods of time
Structure Level Pattern Image Note
TS13: allantois Present 1F right
TS13: future brain Present 1F right
TS13: heart Present 1F right
TS13: embryo Present Ubiquitous 1F right

Specimen 1F left: embryonic day 8.5; Katnb1tm1a(EUCOMM)Hmgu/Katnb1+ (more )
Note: stained for longer periods of time
Structure Level Pattern Image Note
TS13: embryo Present Ubiquitous 1F left
TS13: allantois Present 1F left
TS13: future brain Present 1F left
TS13: heart Present 1F left

Specimen 1G right: embryonic day 9.5; Katnb1tm1a(EUCOMM)Hmgu/Katnb1+ (more )
Structure Level Pattern Image Note
TS15: embryo Present Ubiquitous 1G right
TS15: allantois Present 1G right
TS15: future brain Present 1G right
TS15: heart Present 1G right

Specimen 1G left: embryonic day 9.5; Katnb1tm1a(EUCOMM)Hmgu/Katnb1+ (more )
Structure Level Pattern Image Note
TS15: embryo Present Ubiquitous 1G left
TS15: allantois Present 1G left
TS15: future brain Present 1G left
TS15: heart Present 1G left

Specimen 1H: embryonic day 9.5; Katnb1tm1a(EUCOMM)Hmgu/Katnb1+ (more )
Structure Level Pattern Image Note
TS15: heart atrium Present Ubiquitous 1H
TS15: neural tube Present Ubiquitous 1H
TS15: outflow tract Present Ubiquitous 1H
TS15: primitive ventricle Present Ubiquitous 1H

Specimen 1I right: embryonic day 11.5; Katnb1tm1a(EUCOMM)Hmgu/Katnb1+ (more )
Structure Level Pattern Image Note
TS19: embryo Present Ubiquitous 1I right

Specimen 1I left: embryonic day 11.5; Katnb1tm1a(EUCOMM)Hmgu/Katnb1+ (more )
Structure Level Pattern Image Note
TS19: embryo Present Ubiquitous 1I left

Specimen 1J: embryonic day 11.5; Katnb1tm1a(EUCOMM)Hmgu/Katnb1+ (more )
Structure Level Pattern Image Note
TS19: atrioventricular endocardial cushion Present 1J
TS19: branchial arch Present 1J
TS19: heart atrium Present 1J
TS19: heart ventricle Present 1J
TS19: outflow tract Present 1J
TS19: outflow tract endocardial cushion Present 1J

Specimen 1K: embryonic day 11.5; Katnb1tm1a(EUCOMM)Hmgu/Katnb1+ (more )
Structure Level Pattern Image Note
TS19: heart left ventricle Present 1K
TS19: heart right ventricle Present 1K
TS19: left atrium Present 1K
TS19: outflow tract Present 1K
TS19: right atrium Present 1K


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory