Gene Expression Data
Assay Details
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Assay
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Reference:
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J:121609
Wang C, et al., The Shh-independent activator function of the full-length Gli3 protein and its role in vertebrate limb digit patterning. Dev Biol. 2007 May 15;305(2):460-9
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:6149485
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Gene symbol:
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Grem1
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Gene name:
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gremlin 1, DAN family BMP antagonist
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Results
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Specimen
6U:
embryonic day 10.5
(more  )
Specimen
6U:
(close  )
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Genetic Background:
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involves: 129 * C57BL/6
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
6V:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N
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Mutant Allele(s):
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Gli3tm2Blnw/Gli3tm2Blnw
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: forelimb bud |
Present |
Regionally restricted |
6V
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Ectopic anterior expansion of expression similar to that in Gli3-/- limb buds.
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Specimen
6W:
(close )
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Genetic Background:
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involves: 101/H * 129S1/Sv * 129X1/SvJ * C3H/HeH * C57BL/6 * CBA/H * FVB/N
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Mutant Allele(s):
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Gli3tm2Blnw/Gli3Xt
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: forelimb bud |
Present |
Regionally restricted |
6W
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Ectopic anterior expansion of expression similar to that in Gli3-/- limb buds.
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Specimen
6X:
(close )
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Genetic Background:
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involves: 101/H * 129 * C3H/HeH * C57BL/6 * CBA/H
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Mutant Allele(s):
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Gli3Xt/Gli3Xt
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: forelimb bud |
Present |
Regionally restricted |
6X
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Authors report ectopic anterior expansion of expression
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Specimen
6Y:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N
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Mutant Allele(s):
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Gli3tm1Urt/Gli3tm2Blnw
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: forelimb bud |
Weak |
Regionally restricted |
6Y
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Authors state that ectopic expression was suppressed. Expression is reduced, but still anteriorly expanded.
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Analysis Tools
