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Gene Expression Data
Assay Details
Assay
Reference: J:121609 Wang C, et al., The Shh-independent activator function of the full-length Gli3 protein and its role in vertebrate limb digit patterning. Dev Biol. 2007 May 15;305(2):460-9
Assay type: RNA in situ
MGI Accession ID: MGI:6149484
Gene symbol: Hoxd13
Gene name: homeobox D13
Results
Specimen 6P: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forelimb bud Present 6P
Specimen 6Q: embryonic day 10.5; Gli3tm2Blnw/Gli3tm2Blnw (more )
Structure Level Pattern Image Note
TS17: forelimb bud Present Regionally restricted 6Q Extent of anterior expansion and levels of expression similar to those in Gli3/ limb buds
Specimen 6R: embryonic day 10.5; Gli3tm2Blnw/Gli3Xt (more )
Structure Level Pattern Image Note
TS17: forelimb bud Present Regionally restricted 6R Extent of anterior expansion and levels of expression similar to those in Gli3/ limb buds
Specimen 6S: embryonic day 10.5; Gli3Xt/Gli3Xt (more )
Structure Level Pattern Image Note
TS17: forelimb bud Present Regionally restricted 6S Authors report ectopic anterior expansion of expression.
Specimen 6T: embryonic day 10.5; Gli3tm1Urt/Gli3tm2Blnw (more )
Structure Level Pattern Image Note
TS17: forelimb bud Present 6T Authors state that ectopic expression was suppressed. Nearly normal expression.
Specimen 7F: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forelimb bud Present 7F
Specimen 7G: embryonic day 10.5; Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS17: forelimb bud Absent 7G
Specimen 7H: embryonic day 10.5; Gli3tm2Blnw/Gli3tm2Blnw, Shhtm1Chg/Shh+ (more )
Structure Level Pattern Image Note
TS17: forelimb bud Strong Regionally restricted 7H Expression upregulated and expanded. Authors state ectopic anterior expression was Shh-independent.
Specimen 7I: embryonic day 10.5; Gli3tm2Blnw/Gli3tm2Blnw, Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS17: forelimb bud Strong Regionally restricted 7I Expression upregulated and expanded. Authors state ectopic anterior expression was Shh-independent.
Specimen 7J: embryonic day 10.5; Gli3tm2Blnw/Gli3+, Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS17: forelimb bud Weak 7J
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory