Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Il21tm1.1Kubo
Name:	interleukin 21; targeted mutation 1.1, Masato Kubo
MGI ID:	MGI:6149152
Synonyms:	Il21f, Il21flox
Gene:	Il21  Location: Chr3:37276908-37286785 bp, - strand  Genetic Position: Chr3, 18.36 cM, cytoband B
Alliance:	Il21tm1.1Kubo page

Germline Transmission:	Earliest citation of germline transmission: J:259397
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: Exons 1 and 2 were floxed by loxP sites. A FRT-flanked PGK-Neo cassette was also inserted. FLP-mediated recombination removed the selection cassette. (J:259397)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Il21 Mutation:	40 strains or lines available

Original:	J:259397 Miyauchi K, et al., Protective neutralizing influenza antibody response in the absence of T follicular helper cells. Nat Immunol. 2016 Dec;17(12):1447-1458
All:	1 reference(s)