Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Slc32a1tm2.2Yyan
Name:	solute carrier family 32 (GABA vesicular transporter), member 1; targeted mutation 2.2, Yuchio Yanagawa
MGI ID:	MGI:6148234
Synonyms:	VGAT-
Gene:	Slc32a1  Location: Chr2:158452687-158457668 bp, + strand  Genetic Position: Chr2, 78.72 cM, cytoband H1-3
Alliance:	Slc32a1tm2.2Yyan page

Germline Transmission:	Earliest citation of germline transmission: J:241759
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S/SvEv

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: A loxP site was inserted into intron 1 and an FRT site flanked neomycin resistance gene cassette and a second loxP site into intron 3. Cre mediated recombination removed exons 2 and 3 to create a null allele. (J:241759)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Slc32a1 Mutation:	54 strains or lines available

Original:	J:241759 Saito K, et al., The physiological roles of vesicular GABA transporter during embryonic development: a study using knockout mice. Mol Brain. 2010 Dec 30;3:40
All:	1 reference(s)