Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Slc32a1tm2.1Yyan
Name:	solute carrier family 32 (GABA vesicular transporter), member 1; targeted mutation 2.1, Yuchio Yanagawa
MGI ID:	MGI:6148233
Synonyms:	VGATflox
Gene:	Slc32a1  Location: Chr2:158452687-158457668 bp, + strand  Genetic Position: Chr2, 78.72 cM, cytoband H1-3
Alliance:	Slc32a1tm2.1Yyan page

Germline Transmission:	Earliest citation of germline transmission: J:241981
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S/SvEv

Allele Type:    Targeted (Conditional ready) Mutation:    Insertion   Mutation details: A loxP site was inserted into intron 1 and an FRT site flanked neomycin resistance gene cassette and a second loxP site into intron 3. The neomycin selection cassette was removed via FLP-mediated recombination. This creates a conditional-ready allele with exons 2 and 3 floxed and without the neomycin selection cassette. (J:241981)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Slc32a1 Mutation:	54 strains or lines available

Original:	J:241981 Kayakabe M, et al., Motor dysfunction in cerebellar Purkinje cell-specific vesicular GABA transporter knockout mice. Front Cell Neurosci. 2013;7:286
All:	3 reference(s)